Unit:
Κατεύθυνση Ογκολογία Θώρακα: Σύγχρονη Κλινικο-Εργαστηριακή Προσέγγιση και ΈρευναLibrary of the School of Health Sciences
Author:
Papavasileiou Vasileios
Supervisors info:
Άννα Καρακατσάννη, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπουσα
Ηλίας Κοττέας, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Ιωάννης Γκιόζος, Ακαδημαϊκός υπότροφος, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Παράγοντες κινδύνου για ανάπτυξη λοίμωξης αναπνευστικού μετά από βρογχοσκόπηση σε ασθενείς με καρκίνο του πνεύμονα. Η εμπειρία ενός κέντρου
Translated title:
Risk factors for the developement of pulmonary infection after bronchoscopy in patients with lung cancer. The experience of a center
Summary:
Background: Flexible bronchoscopy and its new methods have revolutionized the era of the diagnosis, staging, and restaging of lung cancer. A rare late complication is post-bronchoscopy respiratory infection. In patients with lung cancer, this type of infection is critical not only due to treatment delays but also because it can lead to treatment cancellation and death.
Methods: We retrospectively studied 182 adult patients with lung cancer who underwent diagnostic bronchoscopy at "ATTIKON” University General Hospital from January 2022 to April 2023. The infection and noninfection groups were compared.
Results: Pulmonary infection after the diagnostic bronchoscopy occurred in 7 patients (3.9%) and included pneumonia in 5 patients, parapneumonic effusion in 1 patient, and empyema in 1, too. We recognized as risk factors for post-bronchoscopy pulmonary infection the personal history of COPD (p=0.046), presence of emphysema in CT thorax (p=0.046), endobronchial lesions which causes stenosis ≥50% of the lumen (p=0.04), disease stage IV of NSCLC (p=0.03) and recent hospitalization for COVID-19 (p=0.04) using multivariate analysis. From our patients, one died due to the pulmonary infection, and 4 they had a delay in starting anticancer treatment of 20 days.
Conclusion: Risk factors were identified as the patient's recent hospitalization (in the last month) for COVID-19 infection, personal history of COPD, the presence of an emphysema on CT scan, the presence of an endobronchial lesion during bronchoscopy causing partial obstruction ≥ 50% of the bronchus with further inability to forward the bronchoscope, and stage IV in NSCLC.
Main subject category:
Health Sciences
Keywords:
Risk factors, Pulmonary infection, Bronchoscopy, Lung cancer
