Unit:
Κατεύθυνση Κλινικές Μελέτες: Σχεδιασμός και ΕκτέλεσηLibrary of the School of Health Sciences
Author:
Koukotsika Magdalini
Supervisors info:
Φλώρα Ζαγουρή, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Ιωάννα Ανδρεάδου, Καθηγήτρια, Φαρμακευτική Σχολή, ΕΚΠΑ
Μαρία Γαβριατοπούλου, Αναπληρώτρια Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Η επίπτωση του καρκίνου του στομάχου στον πληθυσμό, οι διαθέσιμες θεραπείες και η ανάγκη για νέες - καινοτόμες θεραπείες. Βιβλιογραφική ανασκόπηση
Translated title:
The incidence of gastric cancer in the population, the available therapies and the need for new innovative therapies. Α bibliographic review
Summary:
During the recent decades gastric cancer’s incidence has demonstrated a steady decline, especially in populations like the US, Canada and several European countries, on account of the ongoing effort for eradication of Helicobacter pylori which is an important component of the pathophysiology of gastric cancer. Both primary and secondary prevention measures have been adopted towards the achievement of gastric cancer risk elimination, including improved food preservation, personal hygiene and dietary habits and early detection via endoscopic methods respectively. However, it is far from becoming a rare type of cancer, with a high variation in terms of incidence worldwide and with the rates in several countries still experiencing an increasing trend.
The aim of the present thesis is to gather epidemiological data from various studies covering all geographically distinct components of the global rates for gastric cancer and to address the key points of the currently available therapies as well as the future perspectives that could assure a lower mortality and better survival rates for this deathly malignancy.
The revised clinical practice guidelines for the treatment of gastric cancer, published by the National Comprehensive Cancer Network (NCCN) in 2022 pay particular attention to the multidisciplinary treatment of the disease with the cooperation of scientists from different disciplines in order to achieve the best possible outcome for the patient. With the continuous development of scientific research in this field, in recent years targeted therapeutic interventions have given new hope in the effort to treat advanced gastric cancer.
Main subject category:
Health Sciences
Keywords:
Gastric, Cancer, Epidemiology, Therapies
