Assessement of gross motor development in infants with hemophilia using the Alberta Infant Motor Scale (AIMS)

Postgraduate Thesis uoadl:3395930 18 Read counter

Unit:
Κατεύθυνση Γενική και Εξειδικευμένη Παιδιατρική: Κλινική Πράξη και Έρευνα
Library of the School of Health Sciences
Deposit date:
2024-04-17
Year:
2024
Author:
Moschou Christina-Theodora
Supervisors info:
Κουτελέκος Ιωάννης, Αναπληρωτής Καθηγητής, Τμήμα Νοσηλευτικής, ΠΑΔΑ
Περγάντου Ελένη, Διευθύντρια ΕΣΥ, Παίδων Η Αγία Σοφία
Συρεγγέλας Δημήτριος, Τμήμα Παιδιατρικής Φυσικοθεραπείας, Παίδων Η Αγία Σοφία
Original Title:
Αξιολόγηση της αδρής κινητικής εξέλιξης σε βρέφη με αιμορροφιλία με την κλίμακα Alberta Infant Motor Scale (AIMS)
Languages:
Greek
Translated title:
Assessement of gross motor development in infants with hemophilia using the Alberta Infant Motor Scale (AIMS)
Summary:
Assessment of gross motor development in infants with hemophilia using the Alberta Infant Motor Scale (AIMS): Preliminary results

Background: The Alberta Infant Motor Scale (AIMS), is a scale of evaluation, through observation of the gross motor skills of infants, from their birth until independent walking (0-19 months). This tool, has been calibrated according to the Greek population and is able to be used in situations where there is some form of pathology (with certain limitations), but also with healthy infants as a means of observation of their spontaneous motor activity.
Aim: The objectives of this study were 1) to study the gross motor skills of infants with hemophilia, using the Alberta Infant Motor Scale (AIMS) 2) to compare the subsequent results with those of the healthy full term pregnancy infants, so that it can be ascertained whether they fall short in a motor sense compared to the healthy full term pregnancy infants, of the Greek population. Depending on the result, a new direction will be given for further exploration or a therapeutic intervention.
Materials-Methods: For this pilot study, 8 infants were assessed using the Alberta Infant Motor Scale (AIMS), which were being monitored at the Centre of Haemophilia/ Unit of Hemostasis and Thrombosis of Paidon Hospital “Agia Sophia”. The infants were from 6 until 18 months old with normal weight of birth. The sampling was random, since it was composed of infants from different areas of the Attica region and different socio-economic status. For each one of the 8 infants with hemophilia, their score on the AIMS was calculated, which was then used to calculate their z-score and their percentile placement based on their age group. The statistical analysis was performed in two ways. First, one-sample-t-test was utilized to evaluate whether the middle percentile of the sample differed statistically significantly from the median and with independent-sample-t-test was used if the mean percentile of the sample of the infants with hemophilia differed from the sample of healthy full-term pregnancy infants. Furthermore, Mann-Whitney test was used to assess if hemophiliac infants differed compared to healthy full-term pregnancy infants, in reference to the calculated z-scores and the percentile scores on the Alberta Infant Motor Scale (AIMS).
Results: From the statistical analysis, we determine that the middle percentile score of the AIMS on hemophilic infants is only at 4.4%±5.0%, which is significantly less from a statistical point of view compared to the expected median of the 50% (one sample t test,). Similarly, the Mann-Whitney test showed regarding both the percentiles and the z-scores, that there is a statistically important difference between infants with hemophilia and healthy full-term pregnancy infants.
Conclusions: The Alberta Infant Motor Scale (AIMS) is a credible tool of evaluation of the gross motor skills of healthy full term pregnancy infants and full-term pregnancy infants with hemophilia. The statistical analysis showed that there is a significant difference, when it comes to the gross motor development of infants with hemophilia, in comparison with healthy full term pregnancy infants. Further research needs to be conducted with a larger sample and also further investigation into the parameters that affect the gross motor development of infants with hemophilia.

KEYWORDS: Hemophilia gross motor assessment, Alberta Infant Motor Scale, movement evaluation of infants with hemophilia
Main subject category:
Health Sciences
Keywords:
Hemophilia gross motor assessment, Alberta Infant Motor Scale, movement evaluation of infants with hemophilia
Index:
No
Number of index pages:
0
Contains images:
No
Number of references:
90
Number of pages:
114
File:
File access is restricted until 2024-10-17.

Final Thesis Document (1).pdf
2 MB
File access is restricted until 2024-10-17.