Unit:
Κατεύθυνση Διαταραχές της αναπνοής στον ύπνο - Εργαστηριακή και Κλινική Ιατρική του ΎπνουLibrary of the School of Health Sciences
Author:
Kontzialis Theodoros
Supervisors info:
Τρακαδά Γεωργία, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Δικαίος Δημήτριος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Λουτράρη Ελένη, Βιολόγος, Μέλος ΕΔΙΠ, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Σύνδρομο πολυκυστικών ωοθηκών και διαταραχές του ύπνου
Translated title:
Polycystic ovary syndrome and sleep disorders
Summary:
Polycystic ovary syndrome is the most common endocrinopathy across women of reproductive age. Features of the syndrome classically emerge during puberty and include clinical (hirsutism, acne) and laboratory findings of androgen excess, irregular menstrual cycles (oligo-anovulation) and metabolic disorders (obesity, insulin resistance). It is closely related to obstructive sleep apnea syndrome (OSAS) and to other sleep disturbances such as insomnia, poor sleep quality and altered sleep architecture, that may lead to excessive daytime sleepiness (EDS) and to increased cardiometabolic risk. Numerous factors are involved in the etiology of sleep disorders in PCOS, which include sex hormones, obesity, insulin resistance, inflammation, mood disorders and hyperresponsivity of the human stress system (HPA axis). Treatment primarily involves life style changes (healthy diet, physical excersise, cigarette smoke and alcohol avoidance), but also specific for each disorder treatments (CPAP for OSAS, CBT-I for insomnia). Drugs like metformin and oral contraceptives commonly used in PCOS, seem to have a positive effect on sleep disturbances as well.
Main subject category:
Health Sciences
Keywords:
Polycystic ovary syndrome, Sleep disorders, Obstructive apnea, Insomnia
