Unit:
Speciality Infectious DiseasesLibrary of the School of Health Sciences
Supervisors info:
Ευάγγελος Γιαμαρέλλος Μπουρμπούλης, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπων
Αντώνιος Παπαδόπουλος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Ασημίνα Σαφαρίκα, Ακαδημαϊκός Υπότροφος, Ερευνητικό Εργαστήριο Δ Παθολογικής, Αττικόν
Original Title:
Κριτική νόσος COVID-19 και στελέχη Όμικρον SARS-COV-2
Translated title:
Critical COVID-19 infection and Omicron variant SARS-COV-2
Summary:
The COVID-19 virus that first appeared in the city of Wuhan, in China in December 2019, posed a notable threat to the public health. The COVID-19 disease causes a multitude of symptoms such as fever, myalgias, shortness of breath, cough and bad breath. After the emergence of COVID-19, various mutations of the virus led to the creation of various variants of it such as Alpha, Beta and Delta. About 23 months since the first appearance of COVID-19 disease, a new strain of the virus made its appearance in the South Africa, which according to the World Health Organization was categorized as Omicron strain (B.1.529). This variant has a significantly large multitude of mutations, many of them in the spike protein of the virus and therefore it is associated with immune evasion as well as increased transmissibility. In this master thesis, we examine the immune tolerance that the Omicron variant demonstrates compared to the other variants of concern.
Main subject category:
Health Sciences
Keywords:
Wuhan, Alpha, Delta, Omicron, Strain, Immune, Response, Humoral, Escape, Antibody, Mutations, Cytokines, Chemokines, Anakinra
