Unit:
Κατεύθυνση Κλινικοπαθολογοανατομική θεώρηση των νεοπλασιών του ανθρώπουLibrary of the School of Health Sciences
Supervisors info:
Χαρίκλεια Γακιοπούλου Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Ανδρέας Λάζαρης ,Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Αικατερίνη Παυλάκη Ομότιμη Καθηγήτρια, Ιατρική Σχολή ΕΚΠΑ
Original Title:
Εκδηλώσεις παρανεοπλασματικών συνδρόμων στο νεφρικό παρέγχυμα
Translated title:
Affects of paraneoplastic syndromes in kidney
Summary:
Auche described in 1890 the first report of paraneoplastic syndrome with involvement of the peripheral nervous system in patients with cancer. However the word “paraneoplastic” was first used only in 1949 by Guichard and Vignon, when they discussed the differential diagnosis of a patient with central and peripheral neuropathies caused by metastasis of a cervical neoplasia. Nowdays the expression “paraneoplastic syndrome” is defined as a group of symptoms that may develop when substances released by some cancer cells disrupt the normal fuction of surrounding cells and tissue. Paraneoplastic renal symdromes are diseases that indirectly compromise tibular and glomerular fuction by electrolyte imbalance, hormone-producing tumors or deposition of antigen-antibody complexes in the glomeruli. Renal function can be affected by many paraneoplastic syndromes causing hypercalcemia in malignancies, tumor lysis syndrome, renin-producing tumors and paraneoplastic glomerulopathies. An early diagnosis and effective treatment might improve quality of life and change prognosis of these patients.
Main subject category:
Health Sciences
Keywords:
Paraneoplastic syndrome, Kidney, Glomerulopathy, Nephrotic syndrome
Number of references:
120
