Τομέας Υγείας - Μητέρας - Παιδιού
Library of the School of Health Sciences

2013-06-19

2013

Ορφανάκου Αρχοντούλα

Παπαευαγγέλου Β., Κωνσταντόπουλος Α., Καττάμης Α.

Αξιολόγηση νεότερων βιοχημικών δεικτών σε παιδιά με καρκίνο και εμπύρετη ουδετεροπενία

Greek

Purpose: febrile neutropenia in pediatric oncology patients require prompt
management. This thesis examines the prognostic value of several biochemical
markers in identifying the severity of infection.
Methods: we enrolled 17 pediatric cancer patients (20 febrile episodes) with
fever and neutropenia and 20 control patients with fever and measured CRP, PCT,
MIF, NGAL at onset of fever and 2 days later. Cancer patients were divided into
2 groups based on diagnosis of fever: severe bacterial infection and viral
infection or FUO. Control patients were divided into 3 groups: severe bacterial
infection, focal infection and viral infection or FUO.
Results: PCT is statistically higher in cancer patients with severe bacterial
infection at onset of fever and 2 days later.MIF at onset of fever and NGAL 2
days later are also significantly higher in patients with severe bacterial
infection.
Conclusion: PCT has prognostic value in identifying severity of infection, but
also MIF and NGAL seem promising.

fever, neutropenia, cancer, markers, procalcitonin

No

0

Yes

139

101

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https://pergamos.lib.uoa.gr/uoa/dl/object/1305788