Effectiveness of photocoagulation on retinopathy of preterm neonates

Postgraduate Thesis uoadl:1310228 327 Read counter

Unit:
Κατεύθυνση Κλινική Παιδιατρική & Νοσηλευτική - Έρευνα
Library of the School of Health Sciences
Deposit date:
2014-07-25
Year:
2014
Author:
Κουστούκη Βασιλική
Supervisors info:
Καθηγήτρια Παιδιατρικής της Ιατρικής Σχολής ΕΚΠΑ Μπακούλα - Τζουμάκα Χρύσα
Original Title:
Αποτελεσματικότητα της φωτοπηξίας στην αμφιβληστροειδοπάθεια των προώρων νεογνών
Languages:
Greek
Translated title:
Effectiveness of photocoagulation on retinopathy of preterm neonates
Summary:
Introduction: Laser photocoagulation is the treatment of choice for the
treatment of retinopathy of prematurity but the results are not always
favorable.
Purpose: The present study aims to determine the effectiveness of laser
photocoagulation for the treatment of retinopathy of prematurity
Material and Methods: Preterm neonates with gestational age32postmenstrual
weeks and birth weight1500gr, who were treated in the A and B neonatal
intensive care unit in Agia Sofia Children's Hospital from May 2004 to May 2009
were enrolled in the study.
Results: In the study period a total of 312 premature neonates developed
retinopathy of prematurity of which 165 were boys and 147 girls. Birth
weight(BW) of the neonates subjected to laser photocoagulation were between
501-1000gr for 88 babies, 20 were between 1001-1200gr and 12 were between
1201-1500gr while gestational age were<28weeks for 92, 26 neonates were between
28.1 to 30.0weeks, and two were betwwen 30.1 to 32weeks. Newborns who were in
the period 31-60 days were the group most often receiving treatment p<0,001. It
is worth noting that 262 infants did not undergo any surgery, 106 neonates had
1 procedure, 16 infants had 2 and there was a neonate who had three surgeries.
The majority of cases is 95.6% of cases undergoing photocoagulation had
complete recovery, while 4.1% of cases had a negative outcome. The results of
the follow up after 12 months showed that stravismus was seen in 24.7%,
followed in frequency by refractive lesion (15.3%) while reduction in visual
acuity occurred in 4% with blinding of one or both eyes complicating disease in
nine infants(3.1%).
Conclusion: Retinopathy of prematurity is often complicated with structural
defects, refractive anomalies and impaired visual acuity and while laser
photocoagulation is effective in preventing blindness, there were some cases
that needed more than one procedure.
Keywords:
Retinopathy of prematurity, Preterm neonates, Toxic effect of oxygen, Low birth weight, Laser photocoagulation
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
245
Number of pages:
113
File:
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