Κατεύθυνση Μεταβολικά Νοσήματα των Οστών
Library of the School of Health Sciences

2013-02-22

2013

Θεοδωρακοπούλου Σταματία

Επίκουρος Kαθηγήτρια Ευανθία Κασσή

Αρθρικές και παρααρθρικές εκδηλώσεις χρόνιας νεφρικής νόσου

Greek

Articular and paraarticular disorders of chronic kidney disease

The musculoskeletal complications of chronic kidney disease affect the
patient’s overall health because of the direct and indirect effects on quality
of life. Articular and paraarticular manifestations include osteoporosis,
dialysis related amyloidosis (DRA), microcrystal arthropathy, muscoskeletal
infections and fractures, myopathy and nephrogenic systemic fibrosis.
Dialysis-related amyloidosis is a serious complication in chronic dialysis
patients. Its clinical expression in terms of arthralgias, destructive
arthopathies, carpal tunnel syndrome, shoulder peri-arthritis, is often
associated with amyloid deposits in osteoarticular tissues, which are composed
of beta2-microglobulin (beta2-M) fibrils. Treatment is based on reduction of
accumulation of beta2microglobulin and renal transplantation. Crystal-induced
arthropathy causes acute arthritis. The incidence of bone and joint
infections is increased in patients on hemodialysis. Bone disease is a common
complication after kidney transplantation and includes osteoporosis,
osteonecrosis of the femoral head, bone pain syndrome by inhibitors of
calcineurin and gout. In summary, comprehensive assessment and individualized
treatment plan are highly recommended for these patients.

Articular disorders, Paraarticular disorders, Chronic kidney disease, Dialysis related amyloidosis, Microcrystal arthropathy

Yes

7-10

Yes

235

108

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https://pergamos.lib.uoa.gr/uoa/dl/object/1310262