Κατεύθυνση Φυσική των Υλικών (ΒΑΣΙΚΗ ΦΥΣΙΚΗ)
Library of the School of Science

2014-06-10

2014

Παπανικολόπουλος Αλέξανδρος-Νικόλαος

Κ. Ευταξίας Καθηγητής, Δ. Σταμόπουλος Συνεργαζόμενος Ερευνητής

Ενδοκυτταρικα μαγνητικά τροποποιημένα ερυθρά αιμοσφαίρια ως σκιαγραφικοί παράγοντες στη μαγνητική τομογραφία

Greek

Intracellular magnetic modified red blood cells as contrast agents in magnetic resonance imaging

In the present study we propose that magnetically modified red blood cells
(mmRBCs) can be used as a new cellular contrast agent (cCA) in magnetic
resonance imaging (MRI). This new cCA is expected to improve the contrast of
the images in MRI and to enable the imaging of the cardiovascular system for a
long period of time (dozens of days). The magnetic modification of the RBCs was
achieved with two different ways: (A) reducing the hemoglobin of the RBCs and
(B) entrapping nanoparticles of magnetite (Fe3O4). The experimental procedure
was studied with various techniques of microscopy (optical microscope, atomic
force microscope, scanning electron microscope) and with superconducting
quantum interference device. We concluded that it is possible to compound
mmRBCs with relative fast and easy techniques.

Contrast agent, Magnetic resonance imaging, Erythrocytes, Atomic force microscope, Superparamagnetic nanoparticles

No

0

Yes

43

106

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https://pergamos.lib.uoa.gr/uoa/dl/object/1317222