Unit:
Κατεύθυνση Βιολογική ΩκεανογραφίαLibrary of the School of Science
Supervisors info:
1) Καραγιάννη Ήρα, Επίκουρη Καθηγήτρια, Υδρολογία, Πανεπιστήμιο Ιωαννίνων, Συνεπιβλέπουσα.
2) Τσαγκάρη Κατερίνα, Αναπληρώτρια Ερευνήτρια, Οικοτοξικολογία, Ελληνικό Κέντρο Θαλασσίων Ερευνών (ΕΛΚΕΘΕ) , Συνεπιβλέπουσα.
3) Νικολαίδου Άρτεμις, Ομότιμη Καθηγήτρια,Τμήμα Βιολογίας, Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών, Μέλος.
Original Title:
Επιδράσεις φαρμακευτικών ουσιών και μικροπλαστικών στο μύδι Mytilus galloprovincialis, Lamarck 1819
Translated title:
Effects of pharmaceuticals compounds and microplastics on mussels Mytilus galloprovincialis Lamarck 1819
Summary:
an use but also for treating household animals. Microplastics are also well used in daily life mainly as a cosmetic ingredient. They are transported in the marine environment via urban sewage. The fate of those compounds is unknown and provokes many questions about their effects on marine organisms.
The present study aimed to examine the responses of a typical marine bioindicator, the filter feeding Mytilus galloprovincialis, towards pharmaceutical compounds and microplastics. The mussels were exposed for 29 days to 1,5μg/ L clarithromycin, 0,5 μg/ L venlafaxine, 0,8 mg/ L microplastics and the mixture of the forementioned under laboratory conditions, and they were investigated for different sublethal responses. A set of biomarkers indicative of neurotoxicity (acetycholinesterase), oxidative stress (catalase) and biotransformation (glutathione S transferase) was applied.
Results showed effects of clarithromycin and venlafaxine exposure on catalase activity of mussels and effects of venlafaxine and polysterene microplastics on glutathione S transferase activity, suggesting induction of antioxidant defense and/ or biotransformation. Acetycholinesterase activity did not show any significant differences among mussels exposed to pharmaceuticals or microplastics and control ones.
Overall, our results support the hypothesis that human pharmaceuticals can lead to significant effects on non-target species and that bivalve mollusks may represent sensitive organisms for the action of these compounds in the environment. A more integrated study on the effects of pharmaceutical compounds and microplastics could include the use of more biomarkers and the extent of the exposure period.
Main subject category:
Science
Other subject categories:
Oceaonography
Keywords:
clarithromycin, venlafaxine, polystyrene, microplastics, biomarkers, M. galloprovincialis
Number of references:
137
