Τομέας Βασικών Επιστημών
Library of the School of Health Sciences

2018-01-25

2018

Kougias Marios

Kοτανίδου Αναστασία, Καθηγήτρια,Ιατρική , ΕΚΠΑ
Κουτσιλιέρης Μιχαήλ, Καθηγητής,Ιατρική, ΕΚΠΑ
Κυριακοπούλου-Λυμπέρη Μαρία,Καθηγήτρια,Ιατρική, ΕΚΠΑ
Κουλούρης Νικόλαος, Καθηγητής,Ιατρική, ΕΚΠΑ
Σιάσος Γεράσιμος, Αναπληρωτής Καθηγητής,Ιατρική, ΕΚΠΑ
Αγγελογιάννη Παναγούλα, Αναπληρώτρια Καθηγήτρια ,Ιατρική,ΕΚΠΑ
Φιλίππου Αναστάσιος,Επίκουρος Καθηγητής,Ιατρική, ΕΚΠΑ

Η άμεση επίδραση του καπνίσματος στη λειτουργικότητα του αναπνευστικού,στα στηθακουστικά ευρήματα και στο εκπνεόμενο μονοξείδιο του αζώτου (ΝΟ) σε νεαρούς ενήλικες

Greek

The immediate effects of smoking in pulmonary function testing,breath sound analysis and exhaled nitric oxide (NO) in young adults

Smoking detrimentary effects on virtually every organic system, including the respiratory system are well known.

The immediate effects of smoking a single cigarette in young, “healthy” smokers are not well established yet. Novel methodologies of pulmonary function testing, such as Impulse Oscillometry (IOS) and Fractional Exhaled Nitric Oxide (FeNO) measurement, would be very useful means to conduct the study.

Impulse Oscillometry provides accurate measurement of mechanical respiratory parameters, with virtually no cooperation required by the patient. Fractional Exhaled Nitric Oxide measurement is a potentially important meauserement of the inflammatory status of the respiratory system. The abovementioned methodologies are complemantery to standard pylmonary function testing, including spirometry and body plethysmography.

Consequently 50 “healthy” smokers, aged 18-26 years old volunteered to participate in our study. Measurements including IOS, FeNO and conventional pulmonary function testing were performed before and immediately after smoking a single cigarette of their usual brand.

Respiratory impedance, measured by using IOS rised by 7.5%, resistance of the central and peripheral respiratory airways augmented by9,5% and 4% respectively.
FeNO decreased by 14%.

Respiratory sound analysis was also perforemed in group of 18 volunteers, demonstrating a significant variation of crest factor, a well established measurement of sound analysis.
In conclusion, smoking of a single cigarette in young adult “healthy” smokers has an immediate effect in respiratory mechanics, respiratory sound properties and on exhaled Nitric Oxide.

Health Sciences

Smoking, Pulmonary function testing, Impulse oscillometry, Exhaled nitric oxide, Respiratory physiology

No

0

Yes

90

106

File access is restricted only to the intranet of UoA.

https://pergamos.lib.uoa.gr/uoa/dl/object/2632228