Unit:
Κατεύθυνση Σακχαρώδης Διαβήτης και ΠαχυσαρκίαLibrary of the School of Health Sciences
Supervisors info:
Ευάγγελος Λυμπερόπουλος, Αναπληρωτής Καθηγητής, Ιατρικό Τμήμα, Πανεπιστημίο Ιωαννίνων
Αλέξανδρος Κόκκινος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Νικόλαος Τεντολούρης, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Αποτύπωση φαρμακευτικής αγωγής, γλυκαιμικής ρύθμισης και παραγόντων κινδύνου σε διαβητικούς ασθενείς τύπου 2 που παρακολουθούνται σε διαβητολογικό ιατρείο και η μεταβολή τους μετά από 6 μήνες παρέμβασης.
Translated title:
Treatment patterns and the evaluation of glucose and other risk factors control in patients with type 2 DM who attend a diabetes outpatient center of a General Hospital in Attica as well as their change after 6 months.
Summary:
BACKGROUND: The evaluation of glucose and other risk factors control in patients with type 2 DM who attend a diabetes outpatient center of a General Hospital in Attica as well as their change after 6 months.
AIM AND METHODS: Consecutive patients with type 2 DM who attended the diabetes outpatient center of “Amalia Fleming” General Hospital over a 6 months period were included. All patients were treated with antidiabetic drugs. Data were obtained by oral interview and patient files. RESULTS: A total of 175 patients were recorded: 96 men and 79 women, mean age 66.6 ± 10.6 years, diabetes duration 12.5 ± 8.6 years and BMI 33.2 ± 7.1 Kg/m2. Of patients, 20.6% were active smokers and 24.6% consumed alcohol regularly. An annual check for retinopathy was performed in 55.4% of patients and for neuropathy in 22.3%. Of participants, 54.9% had influenza vaccine and 44.6% reported pneumococcal immunization. Antihypertensive treatment was prescribed in 66.3% and hypolipidemic treatment in 56.6% of subjects. Of patients, 65.1% checked their glucose level daily, but only 36% brought measurements for evaluation. Metabolic markers were tested for target achievement in two visits: HbA1c <7% (61.2 vs 62.1% in the baseline and 6 months later visit, p<0.05), LDL-C <70 mg/dL in very high risk patients (17.2 vs 18.4%, p<0.05) and TGs <150 mg/dL (53.9 vs 55.9%, p<0.05). Arterial blood pressure <140/85 mmHg was achieved in 84.8 and 81.1% of patients at baseline and 6 months later (p<0.05). The most frequent medication was metformin (77.7%), followed by DPP-4 (67.4%) and SGLT2 inhibitors (31.4%). SGLT2 inhibitors had the largest increase in use during the 6-month follow-up (7.7%, p<0.05). The most frequent reason for changing drug prescription was treatment failure (67.2%), while the choice of the new antidiabetic agent was mainly influenced by drug potency (58.1%). CONCLUSIONS: Increased efforts are required to ensure that the majority of diabetic patients achieve optimal metabolic regulation and undergo appropriate screening and vaccinations.
Main subject category:
Health Sciences
Keywords:
Diabetes Mellitus, Multifactorial treatment, Risk factors, Metabolic regulation, Screening
