Unit:
ΠΜΣ Σακχαρώδης Διαβήτης και ΠαχυσαρκίαLibrary of the School of Health Sciences
Author:
Chatzis Theodoros
Supervisors info:
Μήνα Ψυχογυιού, Επικ. Καθηγήτρια, Ιατρική, ΕΚΠΑ
Νικόλαος Τεντολούρης, Καθηγητής, Ιατρική, ΕΚΠΑ
Αλέξανδρος Κόκκινος, Αν. Καθηγητής, Ιατρική, ΕΚΠΑ
Original Title:
Λοιμώξεις ελκών διαβητικού ποδιού
Translated title:
Diabetic foot infections
Summary:
A cross-sectional study was conducted with a prospective data collection and the study population consisted of 113 diabetic patients who came to the Outpatient Diabetic Foot Clinic with a diabetic ulcer who were followed for 6 months. A total of 77% of the patients were male, median age was 64 years, with an average Hba1c of 7.9%. Of the patients with ulcers 66.4% had an infection, of which 31% were polymicrobial. Gram (-) bacteria (40%) appeared more frequently, while the multidrug resistant pathogens appeared at 13.4%. In 37.6% of the cases, empirical administration of Ciprofloxacin-Clindamycin was preferred. Gram (-) bacteria showed high antimicrobial resistance to penicillins (80%), cephalosporins (55.5%), β-lactams+Inhibitors (46.7%), and fluoroquinolones (28.9%). Gram (+) strains were resistant in penicillins (80%), erythromycin (46.7%), clindamycin (43.3%), ciprofloxacin (43.3%) and fusidic acid MRSA to clindamycin and erythromycin (87.5%), while no strains were resistant to antibiotics like vancomycin, teicoplanin, and linsezolid. The relative probability of MRSA was 5.7 times higher in smokers than non-smokers. 30.1% were diagnosed with osteomyelitis with the diagnosis based mainly on x-rays, and 26.5% of them continued to have osteomyelitis during the follow-up semester. There was a marginal statistically significant relationship between osteomyelitis and MRSA prevalence. In 2.7% of patients, amputation was considered necessary, while patients visited an average of 4.3 times the diabetic foot clinic during the follow-up semester.
Main subject category:
Health Sciences
Keywords:
Infections, Diabetic foot
Number of references:
119
File:
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Chatzis Theodoros-master.pdf
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File access is restricted only to the intranet of UoA.
