New data in the diagnosis and surgical treatment of the neuroendocrine tumors of the pancreas. A systematic review.

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Κατεύθυνση Χειρουργική Ογκολογία
Library of the School of Health Sciences
Deposit date:
Fountas Spyridon
Supervisors info:
Γεώργιος Πολυμενέας, Καθηγητής, Ιατρική, Αρεταίειο, Επιβλέπων
Γεώργιος Φραγκουλίδης, Καθηγητής, Ιατρική, Αρεταίειο
Θεοδοσόπουλος Θεοδόσιος, Αναπληρωτής Καθηγητής, Ιατρική, Αρεταίειο
Original Title:
Νεότερα δεδομένα στη διάγνωση και χειρουργική θεραπεία των νευροενδοκρινών όγκων του παγκρέατος. Μια συστηματική ανασκόπηση.
Translated title:
New data in the diagnosis and surgical treatment of the neuroendocrine tumors of the pancreas. A systematic review.
Pancreatic Neuroendocrine Tumors are a category of tumors with special characteristics that in many cases consist in a diagnostic challenge. The appropriate diagnostic workup it is highly important since determines therapeutic choices, especially for the Surgeon, in a very particular anatomic area.

The purpose of this systematic review is to study and report recent data on biology, diagnostics and treatment of the pancreatic neuroendocrine tumors with particular interest on surgical management. The rest of the therapeutic approaches are not an object of this study.

Material and Methods
Material of this review is selected bibliography that will result from the systematic research on thedata base PubMed and others with inclusion criteria:
1. Data that correspond in a period from January 2012 till September 2018
2. English language used on publication
3. Key words: Pancreatic neuroendocrine tumors, neuroendocrine tumors
In the study will be included the current guidelines from the NationalComprehensiveCancerNetwork (NCCN) and the EuropeanNeuroendocrineTumorSociety ( ENTS).

Diagnosis and histology characteristics are very important when the treatment for the neuroendocrine tumors of the pancreas is chosen. The small number of prospective studies, due to their rarity, does not allow the collection of sufficient evidence in order to improve their classification and treatment. Surgery remains the cornerstone of their treatmentbut recent data are indicating that in specific cases a “wait and see” approach with regular clinical assessment may be an option.
Main subject category:
Health Sciences
Neuroendocrine, Tumors, Pancreas, Surgical, Treatment
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