Emphasizing the social dimensions of the CRISPR gene modification technique

Postgraduate Thesis uoadl:2878520 28 Read counter

Κατεύθυνση Ιστορία των Επιστημών και της Τεχνολογίας
Library of the School of Science
Deposit date:
Papalexis Andreas
Supervisors info:
Αριστοτέλης Τύμπας, Καθηγητής, Τμήμα Ιστορίας και Φιλοσοφίας της Επιστήμης, ΕΚΠΑ
Original Title:
Αναδεικνύοντας κοινωνικές διαστάσεις της τεχνικής γονιδιακής τροποποίησης CRISPR
Translated title:
Emphasizing the social dimensions of the CRISPR gene modification technique
This diploma thesis attempts to examine from a historical point of view the way in which the Crisps / cas9 genetic modification method has emerged, putting biotechnology and its applications at the center of scientific and social interest. Using tools and methodologies of science, technology and society studies, we will try to highlight the evolution of CRISPR / cas9 and its genetic engineering, which is the current example. Looking at the history of biology and medicine as a whole, and the different forms that it has taken in the transition to modernity, as well as the practices it has developed on a periodic basis, we will try to ask some questions about the various social and political transformations that, through CRISPR, country today and are the new big narrative of the scientific medical and biological community.
Initially we will do a periodic review in various faculties and methods of science-technology studies societies in the light of which the work was written. Here is a brief historical review of the history of biology from the first discoveries that gave birth to what we call genetics and that turned biology from a practice of individual practitioners and physicists into the core of experimental and laboratory methodology and a frontier of "scientific objectivity."
Next, we will mention hubs of the history of modern biology, namely genetic engineering and the incorporation of the CRISPR technique into its current position, both as a practice as such and as the great narrative of the era, using as the main sources the issues of the scientific journals Nature and Cell of the last decade.
Finally, we will ask some questions raised by the CRISPR study, and we will try to palpate the construction of some, incomplete, answers.
Main subject category:
gene editing
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