Comparison of the laparoscopic versus open surgery in colorectal cancer in patient aged over 75 years old. Long-term outcomes

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Κατεύθυνση Χειρουργική Ογκολογία
Library of the School of Health Sciences
Deposit date:
Sotirova Ira
Supervisors info:
Θεοδοσόπουλος Θεοδόσιος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπων
Πολυμενέας Γεώργιος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Φραγκουλίδης Γεώργιος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Σύγκριση λαπαροσκοπικής έναντι ανοιχτής χειρουργικής στον ορθοκολικό καρκίνο σε ασθενείς ηλικίας άνω των 75 ετών -Μακροπρόθεσμα αποτελέσματα
Translated title:
Comparison of the laparoscopic versus open surgery in colorectal cancer in patient aged over 75 years old. Long-term outcomes
Colorectal cancer is the second most common cancer in men and third commonest in women of all ages. Life expectancy has increased and this has created a challenge for surgeons today to decide which approach is better for the elderly patient with colorectal neoplastic disease. The benefit of minimally invasive surgery in colorectal cancer patients has been established, however it is not clear whether these benefits apply to older patients as well.
The aim of this study is to present short- and mid-term outcomes in elderly patients, over the age of 75 years, with colorectal cancer who were treated with the laparoscopic approach in comparison with patients that were treated with open surgery in a tertiary hospital.
This is a midterm retrospective study of selected patients over the age of seventy-five who underwent laparoscopic and open surgery for colorectal cancer between January 2013 until December 2018 in a tertiary referral center.
All patients were > 75 years of age, treated for colorectal cancer, and categorized in two groups: Group 1 patients who had open surgery and Group 2, patients underwent laparoscopic surgery.
Demographic, clinical and postoperative data were retrospectively collected and analyzed between the two study groups.

A minimally invasive procedure in colorectal cancer is equally safe in comparison with the open procedure, considering the similar postoperative complication rate (p-value 0.184). The overall hospital stay postoperatively was in favor of the laparoscopic approach (p-value 0.001). The overall survival in short- and midterm outcomes represents equal results among open and laparoscopic surgical access.

Laparoscopic surgery is as safe and implementable approach for the elderly patients with colorectal cancer, with equal oncological results, maintaining the benefit of a shorter postoperative hospital stay.
This retrospective study compared short and midterm outcomes in elderly patients that underwent elective open or laparoscopic surgery for colorectal cancer.
Main subject category:
Health Sciences
Colorectal cancer, Laparoscopic colectomy, Open colectomy, Elderly patients, Retrospective study
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