Supervisors info:
Στυλιανή Κοκόρη, Επίκουρη Καθηγήτρια, Τμήμα Ιατρικής, ΕΚΠΑ, Επιβλέπουσα
Ωραιάνθη Τραυλού, Καθηγήτρια, Τμήμα Ιατρικής, ΕΚΠΑ
Ελισάβετ Γρουζή, Αιματολόγος, Συντονίστρια Διευθύντρια Ν.Υ. Αιμοδοσίας, Α.Ο.Ν.Α. "Ο Άγιος Σάββας"
Summary:
Thrombosis is the presence of blood clot in an artery or vein. This blood clot has the ability to detach from an artery or vein and block, in whole or in part, blood flow to a specific area of the arterial or venous system. Depending on the area of obstruction, this can result in a variety of debilitating or fatal conditions, including stroke and heart attack.
Patients undergoing surgery have an increased chance of developing blood clots in their veins (venous thromboembolism). Thus, it is worth analyzing physiological hemostasis, which includes a set of interactions between coagulation cascade factors and blood cells, with the most important being platelets. As with other types of surgical operations, during surgery using an extracorporeal circulatory pump (CABG), effective prevention (thrombophilia, antiplatelet therapy), before, during and after a cardiothoracic surgery can reduce the risk of postoperative thrombus formation. However, thromboprophylaxis, must be balanced with the associated risks of bleeding. The INR value, which is of great importance, is different for each type of cardiac surgery.
Finally, the emphasis is given on selecting the right combination of anticoagulants with appropriate treatment protocols to avoid the pathogenicity and morbidity of thrombosis in this group of patients.
