Unit:
Κατεύθυνση Παθολογία της ΚύησηςLibrary of the School of Health Sciences
Supervisors info:
Νικόλαος Παπαντωνίου, Ομότιμος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπων
Δημήτριος Κασσάνος, Ομότιμος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Χαράλαμπος Χρέλιας, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Λιστέρια και κύηση
Translated title:
Listreria and pregnancy
Summary:
Listeriosis is a rare foodborne illness caused by listeria monocytogenes. Listeria can be transmitted by consuming ready-to-eat food, long-life products, meat and soft cheeses which are contaminated. People that are more sceptible to be infected by listeria are immunocompromised patients, elderly people, pregnant women and neonates. Specifically, pregnant women are 18 times more susceptible to be infected than general population and the reason is the suppressed cell-mediated immunity and the placental tropism of listeria.
Maternal, fetal and neonatal disease is part of listeriosis in pregnancy. Maternal infection is more often without any symptoms or with mild flu-like symptoms. Fetal listeriosis has high rates of fetal lose, depending on gestational age at the time of infection. Sepsis and/or meningitis can occur at infected neonates and fatality rate can be very high as 20%. Maternal treatment is essential for prevention and therapy of fetus and neonate. The first line therapy are amoxicillin or ampicillin alone or in combination with gentamycin or trimethoprime/sulfomethoxazole.
Infection by listeria should be always considered when a pregnant woman has fever and should be treated. Prevention remains the best way to control listeriosis and should be reinforced among patients, health care professionals, and regulatory agencies.
Main subject category:
Health Sciences
Keywords:
Listeria, Pregnancy
File:
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Vionidi Elena MSc.pdf
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