Immediate post-operative complications occurred in patients undergoing othotopic liver transplantation

Doctoral Dissertation uoadl:2898245 300 Read counter

Unit:
Τομέας Χειρουργικής
Library of the School of Health Sciences
Deposit date:
2020-02-19
Year:
2020
Author:
Kaskantamis Andreas
Dissertation committee:
1.Ευστάθιος Αντωνίου,Αναπληρωτής Καθηγητής Γενικής Χειρουργικής(Επιβλέπων) Β Προπαιδευτική Χειρουργική Κλινική -ΛΑΙΚΟ ΓΝΑ
2.Δημήτριος Μαντάς,Αναπληρωτής Καθηγητής Γενικής Χειρουργικής Β Προπαιδευτική Χειρουργική Κλινική-ΛΑΙΚΟ ΓΝΑ
3.Αλκιβιάδης Κωστάκης,Καθηγητής Γενικής Χειρουργικής 'Ιδρυμα Ιατροβιολογικών Ερευνών,Ακαδημίας Αθηνών
4.Κωνσταντίνος Κόντζογλου,Καθηγητής Γενικής Χειρουργικής Β Προπαιδευτική Χειρουργική Κλινική -ΛΑΙΚΟ ΓΝΑ
5.Γεώργιος Σωτηρόπουλος,Αναπληρωτής Καθηγητής Γενικής Χειρουργικής Β Προπαιδευτική Χειρουργική Κλινική-ΛΑΙΚΟ ΓΝΑ
6.Δημήτριος Δημητρούλης,Αναπληρωτής Καθηγητής Γενικής Χειρουργικής Β Προπαιδευτική Χειρουργική Κλινική-ΛΑΙΚΟ ΓΝΑ
7.Στυλιανός Κύκαλος,Επίκουρος Καθηγητής Γενικής Χειρουργικής, Β Προπαιδευτική Χειρουργική Κλινική -ΛΑΙΚΟ ΓΝΑ
Original Title:
Άμεσες μετεγχειρητικές επιπλοκές σε ασθενείς με ορθοτοπική μεταμόσχευση ήπατος
Languages:
Greek
Translated title:
Immediate post-operative complications occurred in patients undergoing othotopic liver transplantation
Summary:
Orthotopic Liver Transplantation (OLT) is the treatment of choice for patients with end stage liver disease, acute liver failure, hepatocellular carcinoma and metabolic disorders. As a result of improvement in surgical and anesthesiological skills, advanced understanding of transplant immunology and better critical care management of complications, patients survive longer after liver transplantation. It has been gradually achieved one-year survival rates of 80-90%. During the early post-operative period, all patients undergoing OLT are admitted to the intensive care unit, as they need a management of both preexisting patient’s conditions and post-operative complications, usually due to either adverse intra-operative or post-operative events. The purpose of this review is the detailed recording, understanding and interpretation of immediate post-operative complications occurred in patients undergoing OLT, in intensive care unit. This could help to improve patient’s treatment and reduce the incidence of complications, with further reduction of morbidity-mortality and cost. We also present our experience from the first 32 OLT patients from Liver Transplantation Unit of Laiko General Hospital, the only Liver Transplantation Unit in Athens. We also use all the results from our 32 patients from our Liver Transplantation Unit during the period 07/2006 to 07/2009. All patients undergoing OLT admitted to the intensive care unit for a period of time, depending on the occurrence of post-operative complications. The incidence of primary failure ranges between 2-14%, whereas post-operative bleeding ranges between 7-15%. The treatment is usually conservative, although surgical repair may need in 10-15%. Acute renal failure post-operative is not an infrequent problem too, and has been reported to occur in 66% of cases. Acute rejection normally occurs 7-14 days after OLT. Additionally, the delay of the weaning from mechanical ventilation in the immediate post-operative period could increase the complications. Infectious complications are quite common almost from the first post-operative day in intensive care unit. Prolonged intensive care stay could increase the complications post-operative Infectious complications, renal and respiratory impairment are among the most common causes of early post-transplant morbidity and mortality.
Main subject category:
Health Sciences
Keywords:
orthotopic-Liver-Transplantation-Intensive-Care-Unit-Post operative-Complications-Outcomes
Index:
No
Number of index pages:
0
Contains images:
Yes
Number of references:
143
Number of pages:
97
File:
File access is restricted only to the intranet of UoA.

KASKANTAMIS ANDREAS PhD.pdf
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