Κατεύθυνση Επεμβατική Καρδιολογία
Library of the School of Health Sciences

2020-06-22

2020

Moustogiannis Georgios

Δμήτριος Τούσουλης, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ, Επιβλέπων
Ελένη Κυρίτση, Ομότιμη Καθηγήτρια, Τμήμα Νοσηλευτικής, Τ.Ε.Ι. Αθήνας
Κωνσταντίνος Τούτουζας, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ

Σύγκριση των αρρυθμιολογικών συμβαμάτων κατά τη διάρκεια δυναμικής σπινθηρογραφικής μελέτης αναφορικά με το επίπεδο καρδιακής φόρτισης, το βαθμό ισχαιμίας και την ανατομική εντόπιση των τοιχωμάτων της αριστερής κοιλίας

Greek

Correlation of arrhythmic events occurring during myocardial perfusion imaging using SPECT (single-photon emission computed tomography) according to cardiac stress level, ischemia extent and anatomic location in left ventricular walls

Background:Myocardial perfusion imaging using single-photon emission computed tomography (SPECT) is a complex stress test, widely used in routine clinical practice, aiming at detecting the presence of coronary artery disease or documenting its progression.
Objective:The primary objective of the present study is to investigate the incidence of arrhythmic events occurring during myocardial perfusion imaging using SPECT in relation to: a. cardiac stress level; b. ischemia or necrosis extent; and c. anatomic location of ischemia in left ventricular walls.
Material and methods:Myocardial perfusing imaging using SPECT was performed in 151 patients; electrocardiographic and imaging findings were recorded and analysed. The correlation between categorical variables was assessed usingx2-test. A P value of 0.05 determined two-sided statistical significance.
Results:Mean age of study population was 69.8 years. The observed events included single ventricular ectopics (19.2%);pairs of ventricular ectopic beats (5.3%); supraventricular ectopics (4%); atrial fibrillation (1.3%); polymorphic ventricular ectopics (1.3%); and non-sustained ventricular tachycardia (1.3%). All patients reached ≥4 METs. 58.3% of patients had mild ischemia extent and 21.2% of patients had moderate ischemia extent. 25.2% of patients showed limited area of necrosis, 14.6% moderate and 6.6% severe. Most patients showed necrotic areas in two regions of left ventricular walls, with most common locations the inferior, the apical, the lateral and the anterior walls. The correlation between ischemia extent and single ventricular ectopics, as well as between apical ischemia and single ventricular ectopicsshowed marginal statistical significance (P=0.1). Apical ischemia and pairs of ventricular ectopicsshowed significant
correlation (P=0.03). Ischemia located in interventricular septum correlated significantly to supraventricular ectopy (P=0.03). Inferior wall necrosis also correlated to supraventricular ectopy (P=0.04).
Conclusion:The present study has demonstrated that arrhythmic events are more common in the presence of ischemia or necrosis in more than one wall, as well as in higher stress level. Furthermore, there is a definite correlation between the location of ischemia/necrosis in left ventricular walls and the nature of arrhythmic events.

Health Sciences

SPECT, Arrhythmia, Myocardial ischemia, Myocardial necrosis, Left ventricular walls

No

0

Yes

63

66

File access is restricted only to the intranet of UoA.

https://pergamos.lib.uoa.gr/uoa/dl/object/2917126