Κατεύθυνση Παθολογία της Κύησης
Library of the School of Health Sciences

2020-11-09

2020

Sfakianakis Antonios

Παπαντωνίου Νικόλαος, Ομότιμος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Κασσάνος Δημήτριος, Ομότιμος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Συριστρατίδης Χαράλαμπος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ

Επανειλημμένες αποβολές, σύγχρονη διάγνωση και θεραπεία

Greek

Recurrent miscarriages, current diagnosis and treatment

Introduction: Repeated pregnancy loss is an important issue in reproductive health, affecting 2-5% of couples. Common proven causes include uterine abnormalities, antiphospholipid syndrome, hormonal and metabolic disorders, and cytogenetic abnormalities. Other causes have been suggested but are still controversial, such as chronic endometritis, hereditary thrombophilia, lumbar phase deficiency and high levels of sperm DNA fragmentation.
Individual examinations appropriate for each woman or couple based on age, fertility / sub- fertility, the patient's history, family history, previous examinations and / or treatments should be individually assessed.
Purpose - Materials and Method: RPLs are considered a pathological condition associated with heterogeneous laboratory and clinical findings, and are also linked to subfertility. An attempt is made to rank parameters derived from past history and diagnostic results with regard to the prognosis, as well as to provide the main data, evidence and research conclusions, to give a comprehensive picture of how to treat the condition.
To collect the data, the online literature was searched with PubMed and GoogleScholar search engines. The search results were analyzed and those relevant were identified in order to be included. Conclusions: Providing information and performing examinations do not necessarily lead to successful outcome. Staff have the right skills to understand the patient's concerns, but it should be made clear that there may not always be treatments available. Over the years, evidence-based treatments, have improved outcomes for couples with recurrent pregnancy loss. However, a significant number of cases remain unexplained and empirically treated. Despite the difficulties, the long-term prognosis of couples with recurrent pregnancy loss is favourable and most eventually achieve a healthy live birth. There are, of course, many efforts being made to improve treatments and reduce the time required for successful pregnancy. In many areas there is limited evidence and an
urgent need for further studies.

Health Sciences

Recurrent pregnancy loss, Idiopathic, Genetic polymorphism, NK cells, Uterine anatomic abnormality, Follicle stimulating hormone, Antiphospholipid syndrome

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https://pergamos.lib.uoa.gr/uoa/dl/object/2924352