Unit:
Faculty of MedicineLibrary of the School of Health Sciences
Dissertation committee:
Αντωνία Κουτσούκου, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ (Επιβλέπουσα)
Αναστασία Κοτανίδου, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Νικολέττα Ροβίνα, Επίκουρη Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Στυλιανός Ορφανός, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Ιωάννης Βασιλειάδης, Επίκουρος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Παρασκευή Κατσαούνου, Επίκουρη Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Γαρυφαλλιά Πουλάκου, Επίκουρη Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Η επίπτωση της οικογενούς υπερχοληστεροναιμίας στον ελληνικό πληθυσμό
Translated title:
Prevalence of familial hypercholesterolemia on the Greek population
Summary:
Introduction: Cardiovascular disease is the leading cause of morbidity and mortality worldwide. Non-modifiable risk factors include familial hypercholesterolemia. The underdiagnosis of the disease has as its first manifestation cardiovascular events. In Greece it is estimated that 90% of patients remain undiagnosed.
Aim: The aim of the present study was towas to investigate the impact of the disease on the Greek population. Also, to investigate the clinical features and predisposing factors of the disease.
Material and Methods: This is a contemporary observational study. The study was conducted in the years 2016-2019. The sample consisted of Greek citizens residing in the prefecture of Attica. The individuals were randomly selected in order to increase the representativeness of the sample. 1849 people were collected, of which 271 were excluded because there was no complete information for the examination of Simon Broom criterion of the diagnosis of familial hypercholesterolemia. The information was recorded by personal interview and included socio-demographic and somatometric characteristics, clinical characteristics and individual habits. For data processing, the statistical package SPSS ver.20 was used.
Results: According to the results of the study, frequency of occurrence FH in Greek population is 1: 198. Also, factors that have a significant correlation with familial hypercholesterolemia is arterial hypertension and BMI.
Conclusions: The prevalence of FH in Greece is unknown. Patients with FH are at high risk for cardiovascular events and death at a young age. Therefore, early detection of these is important for the implementation of appropriate precautionary measures. Patient records are a powerful tool for recording and monitoring disease and promoting clinical practice, thus helping to improve outcomes and reduce the cost of healthcare. Simultaneously with the thighs requires patient-centered management, multidisciplinary teamwork, involvement of primary care physicians, patient networks and support teams
Keywords: Familial hypercholesterolemia, incidence, patient records, physical activity, arterial hypertension, LDL, HDL.
Main subject category:
Health Sciences
Keywords:
Familial hypercholesterolemia, Incidence, Patient records, Arterial hypertension, LDL, HDL
Number of references:
200
