Κατεύθυνση Επεμβατική Ακτινολογία
Library of the School of Health Sciences

2021-02-11

2021

Theodosis Antonios

Σταύρος Σπηλιόπουλος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Νικόλαος Κελέκης, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Δημήτριος Φιλιππιάδης, Επίκουρος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ

Ογκομετρία με Πολυτομική ΥΤ για τον υπολογισμό του ρυθμού αιμορραγίας

Greek

MDCTA Volumetry for the quantification of acute hemorrhage

Purpose
To assess the feasibility of Multi-Detector Computed Tomography Angiography
(MDCTA) volumetry for the quantification and grading of acute, bleeding.
Materials and Methods
This retrospective, single-center, study investigated consecutive patients with
MDCTA positive for active non-cerebral, non-gastrointestinal bleeding, between
January 2020 and June 2020. Outcome measures were the quantification of active
extravasation at the arterial and parenchymal phase using volumetry measurements,
the calculation of active bleeding rate and bleeding grading, 30-day mortality rate,
identification of independent predictors of mortality and correlation between
volumetric analysis, various clinical features and the decision to proceed with an
intervention.
Results
In total 30 patients (17 females; 56.6%; mean age 70.0±16.0 years) were analyzed.
Volumetric analysis was feasible in all cases resulting in excellent inter-observer
variability (interclass correlation coefficient 0.999 for arterial and 0.919 for venous
volume measurements). Mean volume of contrast extravasation was 1.06±1.09ml
and 3.07±2.48 ml at the arterial and parenchymal phases, respectively. Mean
bleeding rate was 6.95±7.82 ml/min. High bleeding volume at arterial phase (grade 4
bleeding) was the only independent predictor of 30-day mortality (HR 1383.58;
p=0.042). There was a positive correlation between bleeding volume at arterial
phase (r s = 0.340; p=0.033) and arterial bleeding rate (r s = 0.381; p=0.019) with the

decision to proceed with an intervention. Bleeding volume of 0.6ml was the cutoff
value for the prediction of intervention (sensitivity 96.3%; specificity 66.7%).
Conclusion
MDCTA volumetric analysis for the quantification and grading of acute hemorrhage
was feasible with excellent inter-observer agreement. The proposed bleeding
grading system could optimize decision making and predict clinical outcomes.

Health Sciences

MDCT angiography, Volumetry, Active bleeding, Acute hemorrhage, Endovascular treatment.

No

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Yes

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https://pergamos.lib.uoa.gr/uoa/dl/object/2933918