Faculty of Medicine
Library of the School of Health Sciences

2021-10-19

2021

Drachtidi Kalliopi

Παρασκευή Ματσώτα, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Γεωργία Γερολουκά-Κωστοπαναγιώτου, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Χρυσάνθη Μπατιστάκη, Αν. Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Σοφία Καλανταρίδου, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Θεοδόσιος Σαραντέας, Αν. Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Τατιάνα Σιδηροπούλου, Αν. Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Περικλής Παναγόπουλος, Επικ. Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ

Επισκληρίδιος αναλγησία ελεγχόμενη από την ασθενή (Patient controlled epidural analgesia – PCEA) με διάλυμα ροπιβακαΐνης 0,15% και φεντανύλης 2 μg/ml κατά τη διάρκεια φυσιολογικού τοκετού. Συγκριτική μελέτη της συνεχούς έγχυσης μαζί με κατ’ επίκληση της επιτόκου χορήγηση σε σχέση με την κατ’ επίκληση μόνο της επιτόκου χορήγηση ως προς την αποτελεσματικότητα και την ικανοποίηση των επιτόκων

Greek

Patient controlled epidural analgesia (PCEA) with solution of ropivacaine 0.15% and fentanyl 2 μg/ml during labour. Comparative study of the background infusion plus demand bolus doses compared to demand bolus doses only respect to efficacy and maternal satisfaction

Patient-Controlled Epidural Analgesia (PCEA) is a common practice for labour pain
relief. This study aimed to compare two different settings of a PCEA device using the
same solution to obtain labor analgesia.
Fifty two parturients were randomly allocated to receive ropivacaine 0.15% and fentanyl
2γ/mL via a PCEA device either as a background infusion of 5mL/h plus 5mL demand
bolus doses with 10 minute lockout (group B/D, n=26) or as only demand bolus doses of
5mL with 10 minute lockout (group D, n=26). The primary outcome was the total volume
of local anesthetic administrated during labour; secondary outcomes included the
analgesic efficacy (VAS scores, Breakthrough pain) and the effects on maternal and
neonatal outcomes.
No statistical difference was observed between the groups concerning demographic
characteristics, duration of first and second stages of labor, labour outcomes,
administration of oxytocin and ephedrine, rescue doses, Bromage scale, maternal side
effects and satisfaction, neonatal Apgar scores and pH. The total volume of local
anesthetic was greater in group B/D compared to group D (p=0.015). Group D exhibited
higher VAS scores than group B/D but a statistically significant difference was detected
only at the end of the second stage (p=0.036) and at 60 min from the test dose
administration (p=0.022). The incidence of breakthrough pain (VAS>4) was higher in
group D compared with group B/D (p=0.035).
During labour the addition of background infusion plus PCEA demand bolus doses
increased local anaesthetic consumption and reduced breakthrough pain without
affecting maternal satisfaction and neonatal outcomes.

Health Sciences

PCEA, Epidural analgesia, Background infusion, Ropivacaine, Fentanyl

No

0

Yes

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https://pergamos.lib.uoa.gr/uoa/dl/object/2961038