Dissertation committee:
Δέσποινα Περρέα, Ομότιμη καθηγήτρια, Ιατρική σχολή, ΕΚΠΑ
Αθανάσιος Μπενέτος, Καθηγητής, Ιατρική σχολή, ΕΚΠΑ
Κωνσταντίνος Τούτουζας, Καθηγητής, Ιατρική σχολή, ΕΚΠΑ
Νικόλαος Νικητέας, Καθηγητής, Ιατρική σχολή, ΕΚΠΑ
Δημήτρης Ηλιόπουλος, Αναπληρωτής Καθηγητής, Ιατρική σχολή, ΕΚΠΑ
Γεράσιμος Τσουρούφλης, Επίκουρος Καθηγητής, Ιατρική σχολή, ΕΚΠΑ
Στυλιανός Κύκαλος, Επίκουρος Καθηγητής, Ιατρική σχολή, ΕΚΠΑ
Summary:
Decreased of left ventricular ejection function affects the quality of life and survival of patients with cardiovascular disease. The purpose of this study is to investigate the relationship between left ventricular dysfunction and the blood plasma ICAM-1 protein in patients with coronary artery disease. This study included 89 patients with coronary artery disease: 68 patients with normal left ventricular ejection fraction (LVEF≥50%) and 21 patients with affected ejection fraction (LVEF<50%). The protein which was measured in patients' peripheral venous blood plasma was ICAM-1. The demographic characteristics of the two groups did not differ (gender, age, BMI). ICAM-1 levels in blood plasma were higher in patients with LVEF <50% than in patients with LVEF≥50%. ICAM-1 could characterize the left ventricular dysfunction of patients with coronary artery disease.
