Unit:
Κατεύθυνση Επιδημιολογία-Μεθοδολογία έρευνας στις βιοϊατρικές επιστήμες, την κλινική πράξη και τη δημόσια υγείαLibrary of the School of Health Sciences
Author:
Papassotiriou Ioannis
Supervisors info:
Φίλιππος Ορφανός, ΕΔΙΠ, Ιατρική Σχολή, ΕΚΠΑ
Βασιλική Μπενέτου, Αναπληρώτρια Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Ελένη Ριζά, Μέλος ΕΔΙΠ, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Η σχέση των διατροφικών προτύπων και του τρόπου ζωής με καρδιομεταβολικούς δείκτες υγείας σε ηλικιωμένα άτομα
Translated title:
The relationship between dietary patterns and lifestyle with cardiometabolic health indices in older adults
Summary:
Introduction: Cardiovascular diseases are the leading causes of morbidity and mortality worldwide. Lifestyle habits, including diet, are important factors that can significantly reduce the incidence of cardiovascular disease.
Objective: To investigate the relationship between dietary patterns as well as a cumulative index of health behaviors with selected cardiometabolic biochemical indicators.
Materials and Methods: The study population consisted of 3,461 men and women aged> 50 years participating in the Health and Retirement Study conducted in the USA. Nutritional data were collected using a semi-quantitative food frequency questionnaire, while Principal Component Analysis was used to determine dietary patterns, and the Mediterranean Diet Score (MDS) was used to determine adherence to Mediterranean diet (MD). Body mass index (BMI), physical activity, smoking, and adherence to the Mediterranean diet were used for the construction of a cumulative health behavior index. Cardiovascular biomarkers assessed included blood levels of glycosylated hemoglobin, HDL-cholesterol, total cholesterol, C-reactive protein (CRP) and cystatin C.
Results: Four dietary patterns, with the two main ones describing a healthy dietary pattern and a Western dietary pattern were found. The MDS index showed that high adherence to MD was negatively correlated with CRP [b = -9.3 (-13.5 – -4.9)] and cystatin C [b = -3.1 (-4.3 – -1.9)]. The cumulative index of healthy behaviors showed a positive correlation with HDL-cholesterol [b = 0.5 (0.1 – 0.9)] and a negative correlation with the ratio of total to HDL-cholesterol [b = -0.7 (-0.3 – -1.1)], CRP [b = -9.0 (-10.6 – -7.3)] and cystatin C [b = -1.0 (-1.5 – -0.6)].
Conclusions: The present study confirms the relationship between diet and specific biochemical indicators that are prognostic factors of cardiovascular health, but also the importance of cumulatively examining lifestyle factors.
Main subject category:
Health Sciences
Keywords:
Nutrition, Dietary patterns, Mediterranean diet, Biomarkers, Cardiovascular diseases, Cystatin C
