Unit:
Department of ChemistryLibrary of the School of Science
Dissertation committee:
Χρήστος Κόκκινος, Αναπληρωτής Καθηγητής, Τμήμα Χημείας Ε.Κ.Π.Α.
Αναστάσιος Οικονόμου, Καθηγητής, Τμήμα Χημείας Ε.Κ.Π.Α.
Μάμας Προδρομίδης, Καθηγητής, Τμήμα Χημείας Πανεπιστήμιο Ιωαννίνων.
Ευάγγελος Μπακέας, Καθηγητής, Τμήμα Χημείας Ε.Κ.Π.Α.
Στέλλα Γηρούση, Καθηγήτρια, Τμήμα Χημείας Α.Π.Θ.
Δημοσθένης Γκιώκας, Αναπληρωτής Καθηγητής, Τμήμα Χημείας Πανεπιστήμιο Ιωαννίνων.
Φώτιος Τσόπελας, Επίκουρος Καθηγητής, Τμήμα Χημικών Μηχανικών Ε.Μ.Π.
Original Title:
Κατασκευή και εφαρμογές τρισδιάστατων εκτυπωμένων διατάξεων για ηλεκτροανάλυση
Translated title:
Construction and implementation of 3D printed devices for electroanalysis
Summary:
The purpose of this PhD thesis is the development of low-cost completed electrochemical devices, entirely fabricated by 3D printing. The devices are composed
of a micro-cell (printed from non-conductive filament) with integrated 3 electrodes
printed by conductive filament and manufactured by a single-step printing process using
a dual extruder 3D printer. The 3D printed devices were applied to the electrochemical
determination of organic compounds and heavy metals, presenting low sensitivity, high
selectivity, short analysis time, while they are suitable for point of need applications.
More specifically, 3D printed integrated devices were fabricated and applied for
the simultaneous electrochemical determination of paracetamol and caffein and for the
determination of quetiapine and colchicine. Besides, 3D printed devices were
constructed for the voltametric determination of heavy metals, such as mercury and
cadmium and for the amperommetric determination of hydrogen peroxide. Also, 3D
printed mini-biosensor were developed for the determination of C-reactive protein and a
flexible wearable 3D printed sensor in the form of ring for the determination of glucose
in biological fluids.
With this applied technology in the fabrication of sensor the main disadvantages
of conventional manufactory method are minimized. In particular, the use of 3D printing
technology significantly reduces the production cost of the devices compared to existing
techniques (such as injection molding, photolithography, screen printing) using desktop sized, portable, domestic and low-cost equipment. The devices are very small in size,
can be designed in various geometries and are produced by non-toxic and disposable
materials. Their overall size is quite small allowing the handling of small sample
volumes and reagents in the microliter (μL) scale.
Main subject category:
Science
Keywords:
3D printer, electrochemical sensors, caffeine, paracetamol, heavy metals, CRP, quetiapine, glucose, colchicine
Number of index pages:
25
Number of references:
182
