Unit:
Κατεύθυνση Γενική και Εξειδικευμένη Παιδιατρική: Κλινική Πράξη και ΈρευναLibrary of the School of Health Sciences
Author:
Giounenioti Chrysoula
Supervisors info:
Δημήτριος Κασίμος Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΔΠΘ
Αθανάσιος Μίχος Καθηγητής , Ιατρική Σχολή, ΕΚΠΑ
Δέσποινα Μπριάνα Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Η επίδραση των ενδοοικιακών ρυπαντών στην εμφάνιση άσθματος και αλλεργικών εκδηλώσεων κατά τη παιδική ηλικία-Συστηματική ανασκόπηση και μεταανάλυση
Translated title:
The impact of indoor environmental pollutants on asth-ma development and allergic manifestations in child-hood - systematic review and meta-analysis
Summary:
INTRODUCTION: In recent years, there has been an increase in asthma and allergic manifestations during childhood worldwide
OBJECTIVE: The aim of the study was to assess the effect of particulate matter with a diameter less than 10 μm, pet allergens and visible mold on the occurrence of asthma and other allergic manifestations, in particular allergic rhinitis, expiratory wheezing and eczema, in children. The ultimate goal was to contribute to the collection of information for the prevention of allergic diseases and the improvement of children's living conditions in the domestic environment.
MATERIAL: The bibliography search was performed in the digital databases PUBMED, COCHRANE CLASSIC and SCOPUS in October 2021 and April 2022 with a limitation on language (Greek, English) and chronology (articles of the last ten years were searched). 2016 studies identified.
METHODS: The data collection was done by 2 researchers independently according to PRISMA 2009. The quality of the studies was assessed using appraisal checklists for cross-sectional studies, cohort studies and control patient studies by 2 investigators inde-pendently. In the meta-analysis, the results were analyzed using either the fixed effects model or the random effects model if the individual results showed significant heterogeni-ty. Statistical analyses performed with IBM SPSS v.28
RESULTS: The statistical analysis shows that overall the presence of visible mold in-creases the risk of allergic manifestations about 28% with OR = 1.28 (95% C.I.: 1.18 – 1.39) and the presence of particulate matter increases the risk of other allergenic manifes-tations about 15% with OR = 1.15 (95% C.I.: 1.10 – 1.20)
CONCLUSION: The results of the study extend existing knowledge, complement the available data for the paediatric population. Larger systematic studies are necessary
Main subject category:
Health Sciences
Keywords:
Child, Home, Allergy, Asthma, Mold, Particulate matter
