Unit:
Faculty of MedicineLibrary of the School of Health Sciences
Author:
Markantoni Vasiliki
Dissertation committee:
Σταμάτιος Γρηγορίου, Επίκουρος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Αλέξανδρος Στρατηγός, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Χριστίνα Αντωνίου, Ομότιμη Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Αλέξανδρος Κατούλης, Καθηγητής, Ιατρικής Σχολής ΕΚΠΑ
Ηλέκτρα Νικολαίδου, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Ευαγγελία Παπαδαυίδ, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Βασιλική Νικολάου, Επίκουρη Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Μελέτη επιδημιολογικών παραμέτρων πολυεστιακής υπεριδρωσίας στον ελληνικό πληθυσμό
Translated title:
Epidimiological study of Multifocal Hyperhidrosis in Greek population
Summary:
Hyperhidrosis is defined as a disorder of pathologic excessive sweating. Primary hyperhidrosis is defined as excessive sweating without an identifiable cause, usually in the palms, soles, and axillae. Despite the fact that hyperhidrosis causes significant emotional, physical, and social discomfort, which negatively impacts the patient’s quality of life, published data regarding this disorder are scarce. The aim of this study was to describe demographic and clinical characteristics, of patients with multifocal primary hyperhidrosis, treatments employed and natural course of the disorder in a real-world setting. Hence, we included and prospectively followed a total of 102 (38 male and 64 female) patients with multifocal hyperhidrosis presenting in a single center specialized outpatient hyperhidrosis clinic for 4 years. According to our results multifocal hyperhidrosis in three localizations affected 45,1% of the patients, followed by two localizations (41,2%). Almost 5% of the patients reported 5 areas affected. Palms and soles were the most prevalent type of hyperhidrosis in the study sample (80,4%) followed by axillae (62,7). Oral oxybutynin was the most common treatment employed, with 84/102 (82.3%) of patients treated with oral oxybutynin either as monotherapy or in combination with topical aluminium salts solutions/topical anticholinergic formulations/BTX-A during the observation period. In conclusion, this real-world study showed that in patients with multifocal hyperhidrosis involvement of three localizations is as common as involvement of two localizations, palmar and plantar involvement is more common than axillae involvement and treatment with oral oxybutynin has significant survivability
Main subject category:
Health Sciences
Keywords:
Multifocal hyperhisrosis, Primary hyperhidrosis, Oxybutynin, HDSS, Quality of Life, Botulinum Toxin
Number of references:
114
