Unit:
Faculty of MedicineLibrary of the School of Health Sciences
Author:
Sotiropulos Konstadinos
Dissertation committee:
Ευγγελία-Μαρία Μόσχου, Αναπληρώτρια Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Δημήτριος Παπακωνσταντίνου, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Ηλίας Γεωργάλας, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Κλειώ Χατζηστεφάνου, Αναπληρώτρια Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Ειρήνη Χατζηράλλη, Επίκουρη Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Πέτρος Πέτρου, Επίκουρος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Κωνσταντίνος Δρούτσας, Επίκουρος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Επίπτωση κυστεοειδούς οιδήματος ωχράς κηλίδας σε γλαυκωματικούς ασθενείς μετά από επέμβαση καταρράκτη
Translated title:
Incidence οf cystoid macular edema after cataract surgery in eyes with glaucoma
Summary:
This study, conducted at the First Ophthalmological Clinic, Medical School of Athens, investigated the impact of cataract surgery on choroidal thickness, especially in patients with glaucoma and edema. The research spanned from May 2018 to May 2022 and involved patients aged 50 years or older undergoing cataract surgery and IOL insertion in the Ophthalmological Clinic of G. Gennimatas Hospital in Athens. The study utilized Swept Source OCT for measurements and found significant changes in choroidal thickness post-surgery.
Purpose:
The primary objective of this research was to examine the effect of cataract surgery on choroidal thickness and to investigate the incidence of postoperative cystoid macular edema in glaucoma patients. The study also aimed to determine the correlation between postoperative cystoid macular edema and the increase in choroidal thickness using Swept Source OCT.
Methods:
A prospective non-randomized study was conducted on patients undergoing cataract surgery and IOL insertion. Participants were categorized into healthy or glaucomatous groups based on specific criteria. Preoperative and postoperative evaluations were performed, including visual acuity, slit-lamp biomicroscopy, and OCT examination. The Deep Range Imaging (DRI) Triton SS-OCT device was used to measure central retinal thickness and CT of the macular area. Data were analyzed using SPSS v.24 statistical software, with various tests applied to determine associations and differences.
Results:
Statistical analysis revealed a significant difference in choroidal thickness in patients before and after cataract surgery. However, no significant difference was observed in choroidal thickness based on the presence of glaucoma or edema, either preoperatively or postoperatively. The study also found no significant difference in choroidal thickness based on the operated eye (right or left).
Conclusions:
Cataract surgery may influence choroidal thickness, especially in patients with underlying eye conditions like glaucoma and edema. Monitoring choroidal thickness in patients with these conditions is crucial post-surgery. While the study offers valuable insights, it has limitations, including a small sample size and a short follow-up period. Future research should address these limitations and further explore the mechanisms behind choroidal thickness changes post-surgery.
Main subject category:
Health Sciences
Keywords:
Cataract surgery, Choroidal thickness, Glaucoma, Macular edema, Swept Source OCT, Postoperative cystoid macular edema
