Κατεύθυνση Παθολογία της Κύησης
Library of the School of Health Sciences

2024-03-26

2024

Gryllaki Melpomeni

Καλανταρίδου Σοφία, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Ευαγγελινάκης Νικόλαος, Διδάκτωρ, Ιατρική Σχολή, ΕΚΠΑ
Παπαϊωάννου Γεώργιος, Διδάκτωρ, Ιατρική, Σχολή, ΕΚΠΑ

Περιορισμός της ενδομήτριας ανάπτυξης

Greek

Restriction of intrauterine development

The limitation of intrauterine growth (IUGR, intrauterine growth restriction or FGR, fetal growth restriction, as it has now prevailed) refers to the condition in which the fetus is unable to reach its genetically determined growth potential. It is therefore not identical with the term "small for gestational age fetus" (SGA, small for gestational age), since the latter category also includes normal small fetuses.To assess the development of the fetuses, we use the most objective method of assessment that exists today, and that is the estimated weight of the fetus in the ultrasound, that is, we first use the biometrics of the fetus. Thus, a small fetus is defined as a fetus whose ultrasound-estimated weight (EFW, estimated fetal weight) is less than the 10th percentile for gestational age. It is obvious that within this group of embryos are included embryos with residual development as well as normal small embryos. The goal is to be able to identify fetuses with residual growth because they are at increased risk of adverse outcome.Fetal growth restriction is a major cause of perinatal morbidity and mortality (1). However, even fetuses in higher percentiles have an increased risk of complications, such as those with an estimated weight between the 10th and 15th percentiles. This is not hard to see since these embryos may have had genetic potential for much higher percentiles and thus be stunted. Small for gestational age (SGA) fetus is therefore a purely numerical/statistical concept. A prerequisite for growth assessment is that the distribution of birth weight for gestational age in the population in question is available and that the gestational age is correctly determined (2), otherwise false positive or negative estimates of fetal growth may occur.FGR and SGA are therefore not synonymous. At least 50% of newborns weighing below the 10th percentile for sex and gestational age at birth will have been fed normally in utero and simply this was their predetermined size. On the other hand, several infants above the 10th percentile will have failed to reach their optimal growth potential, mainly due to placental insufficiency, i.e. intrauterine undernutrition (2).

Health Sciences

Endometrium, Epidemiology, Placenta, Toxoplasma, Comorbidity

No

0

Yes

87

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https://pergamos.lib.uoa.gr/uoa/dl/object/3392686