Unit:
Κατεύθυνση Θρόμβωση-Αιμορραγία-Ιατρική των μεταγγίσεωνLibrary of the School of Health Sciences
Author:
Sotiropoulou Maria-Eftychia
Supervisors info:
Γιαλεράκη Αργυρή, Αναπληρώτρια Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Βαλσαμή Σερένα, Αναπληρώτρια Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Σταμούλης Κωνσταντίνος, Επιστημονικός Συνεργάτης, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Μεταγγισιοθεραπεία στον ορθοπαιδικό ασθενή
Translated title:
Transfusion of allogeneic blood and it's derivatives in orthopedic patient
Summary:
The transfusion of allogeneic blood and its derivatives is a procedure that has several limitations and costs. Despite the fact that transfusions are life-saving medical interventions, they are associated with the occurrence of a large number of side effects and adverse reactions, both allergic and non-allergic, infections and even disturbance of the function of the recipient's immune system. In addition, blood transfusions are associated with an increased post-operative hospital stay and increased morbidity, thus reflecting the combination of medical co-morbidities and the complexity of surgical procedures for patients requiring blood transfusion.
This narrative literature review explored and presented in detail the recent scientific data in relation to the need to perform transfusions and the methods to minimize them when performing the various surgical orhopaedic procedures (both elective and emergent).
The main conclusions of the study include that blood transfusion strategies during orthopaedic surgery vary, depending largely on the type of surgery performed. More conservative transfusion protocols should be adopted in conjunction with the incorporation of standardised blood conservation techniques, which include preoperative iron and/or erythropoietin therapy in selected patients, early discontinuation of aspirin and non-steroidal anti-inflammatory drugs, ensuring the patient's perioperative normothermia, the intraoperative use of tranexamic acid, and of course the systematic use of the restriction threshold as a threshold for transfusions.
The critical scientific study and standardisation of all the above mentioned practices will allow the most effective use of blood products, with the direct result of protecting patients and reducing the final cost of the performed orthopaedic surgery.
Main subject category:
Health Sciences
Keywords:
Blood transfusions, Orthopaedic surgeries
