Unit:
Κατεύθυνση Δημόσια ΥγείαLibrary of the School of Health Sciences
Author:
Kalentzi-Sali Selman
Supervisors info:
Πέτρος Γαλάνης, Επίκουρος Καθηγητής, Τμήμα Νοσηλευτικής, ΕΚΠΑ
Βενετία-Σοφία Βελονάκη, Αναπληρώτρια Καθηγήτρια, Τμήμα Νοσηλευτικής, ΕΚΠΑ
Παρίσης Γάλλος, Ακαδημαϊκός υπότροφος, Τμήμα Νοσηλευτικής, ΕΚΠΑ
Original Title:
Επίδραση πρηνής θέσης σε διασωληνωμένους ασθενείς με covid-19
Translated title:
Effect of prone position on intubated patients with covid-19
Summary:
Introduction: The first infection with SARS-CoV-2 was identified in Wuhan, China, in late December 2019, and it rapidly spread worldwide. Intensive Care Units (ICUs) were the sole facilities capable of managing severe respiratory distress. An important method to improve this condition is placing patients in a prone position.
Aim: Investigation of the impact and potential benefits of prone positioning in intubated patients with SARS-CoV-2 infection hospitalized during the pandemic in Intensive Care Units.
Methods: The study sample consists of all patients admitted to the ICU, intubated, and with confirmed positive PCR Covid-19 (Molecular Coronavirus Detection Test). Exceptions included individuals under 18 years of age and those with negative PCR Covid-19. The recording of cases begins from the moment of ICU conversion to COVID-19 ICU until closure and reconversion to a regular ICU. The total sample was categorized into a group placed in prone position and a group maintained in supine position. The possible outcomes were death and discharge from the ICU.
Results: Out of the total 202 patients, 73 were placed in prone position (36.1%), with an average of 3.3 prone position sessions. There were 135 male patients (66.8%) with an average age of 66.9 years (range 26-96), and the mortality rate observed was 68.5% (n=138). There was no statistically significant relationship between mortality and prone position (p=0.503). The median PaO2/FiO2 ratio before prone positioning increased from 76.0 mmHg to 145 mmHg two hours after prone positioning. The median survival duration in the prone position group was 26 days, while in the non-prone position group, it was 13 days.
Conclusions: Prone positioning of intubated patients significantly improves PaO2/FiO2 and oxygenation. However, it does not appear to improve mortality rates as there was no statistically significant relationship found in mortality between the prone positioning group and the supine positioning group.
Main subject category:
Health Sciences
Keywords:
Prone position, Covid-19, Intubated patients, Intensive Care Unit
