Unit:
Κατεύθυνση Σακχαρώδης Διαβήτης και ΠαχυσαρκίαLibrary of the School of Health Sciences
Supervisors info:
Κωνσταντίνος Μακρυλάκης, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Ευάγγελος Λυμπερόπουλος, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Γεώργιος Φραγκούλης, Επίκουρος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Steroid-induced hyperglycemia
Translated title:
Steroid-induced hyperglycemia
Summary:
This narrative review based on papers on PubMed and Google Scholar ,explores the intricate landscape of steroid-induced hyperglucemia, focusing on its theoretical framework and clinical implications. The General Section elucidates the pathophysiological mechanisms underlying steroid-induced hyperglucemia, emphasizing the multifactorial nature of its development and progression. It delves into the impact of corticosteroid therapy on glucose metabolism, highlighting the pivotal role of glucocorticoids in disrupting insulin sensitivity and pancreatic function. Additionally, the review examines the existing evidence regarding the epidemiology, risk factors, and complications of steroid-related hyperglucemia, providing a comprehensive understanding of its clinical relevance.
In the Specific Section, the importance and purpose of this review are underscored, aiming to consolidate current knowledge, identify research gaps, and propose recommendations for clinical practice. Results reveal significant strides in elucidating the pathophysiology of corticosteroid-associated hyperglycemia and identifying potential therapeutic targets. However, limitations in research methodology and gaps in literature highlight the need for further investigation to optimize prevention and management strategies.
In conclusion, this oveview underscores the complex interplay between corticosteroid therapy and glucose metabolism in hyperglycemia caused by steroids. It emphasizes the importance of tailored interventions and proactive management approaches to mitigate the adverse metabolic effects of corticosteroids. By addressing current research gaps and advocating for evidence-based practices, this review aims to enhance patient care and outcomes in individuals affected by glucocorticoid-induced hyperglycemia.
Main subject category:
Health Sciences
Keywords:
Corticosteroids, Glucocorticoids, Diabetes mellitus, Diabetes, Steroid-induced diabetes, Steroid-induced hyperglycemia, Hyperglycemia, Glucocorticoid-induced hyperglycemia, Metabolic, Side effects, Adverse effects, Insulin resistance, Steroid diabetes, Steroid-associated diabetes, Steroid-related hyperglycemia, Blood glucose levels, Diabetes secondary to corticosteroid use, Insulin, Stress hyperglycemia
Number of references:
102
File:
File access is restricted only to the intranet of UoA.
Soura_Maria_MSc.pdf
2 MB
File access is restricted only to the intranet of UoA.
