Unit:
Κατεύθυνση Αναπνευστική Ανεπάρκεια και Μηχανικός ΑερισμόςLibrary of the School of Health Sciences
Author:
Vasilaki Aikaterini
Supervisors info:
Βαπορίδη Αικατερίνη , Αναπληρώτρια Καθηγήτρια, Ιατρική Σχολή, Πανεπιστήμιο Κρήτης
Κουτσούκου Αντωνία, Καθηγήτρια, Ιατρική Σχολή, ΕΚΠΑ
Χαντζίαρα Βασιλική, Διδάσκουσα, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Παρατεταμένη πρηνής θέση σε ασθενείς με σύνδρομο οξείας αναπνευστικής δυσχέρειας από Covid-19 και άλλα αίτια
Translated title:
Prolonged prone positioning in patients with acute respiratory distress syndrome due to COVID-19 and other causes
Summary:
INTRODUCTION
Prolonged prone position, as a therapeutic strategy for acute respiratory distress syndrome (ARDS), has received considerable attention in recent years. This approach involves positioning patients with ARDS for prolonged periods, exceeding 24 hours, to improve oxygenation and potentially reduce mortality. This practice has gained particular importance during the COVID-19 pandemic, given the increase in ICU admissions and the need for effective management of ARDS.
PURPOSE
This paper aims to investigate through a systematic review the effects of prolonged prone positioning in acute respiratory distress syndrome (ARDS) related to COVID-19 versus ARDS of other etiologies.
MATERIALS – METHODS
This systematic review was designed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The design and implementation of this study included a systematic search of the literature and organization of documents for the review, summary and quality assessment of each study used in this text and finally synthesis of the data and drafting of the report.
RESULTS
Prolonged prone positioning consistently results in improved oxygenation, as evidenced by an increase in the ratio of arterial oxygen partial pressure/inspired oxygen fraction (P/F). This benefit has been seen in both non-COVID-19 and COVID-19 cases of ARDS. While oxygenation is improved, the effects of prolonged prone positioning on other respiratory parameters such as PaCO2, plateau pressure (Pplatue) and static compliance have yielded mixed results. Studies have reported both positive and limited changes in these parameters.
CONCLUSION
While prolonged prone positioning may improve oxygenation and potentially reduce mortality in patients with ARDS, much remains to be learned about its optimal use, patient selection, and long-term impact. Robust, multicenter studies and continued research efforts will be crucial to define the role of prolonged prone position in the management of ARDS.
Main subject category:
Health Sciences
Keywords:
Prolonged prone positioning, Acute respiratory distress syndrome, prone position and Covid-19, Prone position outcomes, Causes of ARDS
