The role of routine repeat computed tomography of the head in patients with mild or moderate traumatic brain injury: A prospective study

Postgraduate Thesis uoadl:3410655 45 Read counter

Unit:
Κατεύθυνση Κλινική και Πειραματική Νευροχειρουργική
Library of the School of Health Sciences
Deposit date:
2024-07-18
Year:
2024
Author:
Politis Anastasios
Supervisors info:
Λάμπης Σταυρινού, Επίκουρος Καθηγητής, Ιατρική Σχολή ,ΕΚΠΑ
Γεώργιος Βελονάκης, Επίκουρος Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Κωνσταντίνος Πόταγας, Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Original Title:
Ο ρόλος της επαναληπτικής αξονικής εγκεφάλου σε ασθενείς με μικρού ή μετρίου βαθμού κρανιοεγκεφαλική κάκωση: Μία προοπτική μελέτη
Languages:
English
Translated title:
The role of routine repeat computed tomography of the head in patients with mild or moderate traumatic brain injury: A prospective study
Summary:
Background: Computed tomography of the head (CTH) is the primary imaging modality in cases of traumatic brain injury (TBI). The role of routine repeat CTH (RRCTH) in the management of mild TBI remains unclear.
Objective: To investigate whether RRCTH within 24-48 hours post-mild TBI affects clinical decision-making and patient management.
Methods: All patients with mild TBI who were admitted to a tertiary care university hospital between June 2022 and January 2024, who did not receive immediate surgery and were subjected to RRCTH routinely within 24-48 hours, were included in the prospective observational study cohort. Patients aged <18 years, those with moderate or severe TBI or neurological comorbidities, or those who were immediately operated or died within the first 24 hours were excluded. Statistical analysis was conducted with the JASP statistical software using Pearson’s chi-squared test, Fisher’s exact test, and the Mann-Whitney U test.
Results: Seventy patients (18 female) with a mean age of 56.20±20.44 years and a mean admission Glasgow coma scale (GSC) score of 14.59±0.67 were included. RRCTH was performed at a mean of 32.35±24.08 hours post-injury. Radiological and neurological deterioration were observed in 22 (31.43%) and 8 (11.43%) patients, respectively. Although radiological worsening was associated with neurological worsening (OR=8.63, 95% CI=1.58- 47.17, P<.001), only one (1.43%) patient underwent surgery based on RRCTH findings alone. Conclusion: RRCTH within 24-48 hours post-injury for patients with mild TBI is associated with clinical deterioration but does not affect their management.
Main subject category:
Health Sciences
Keywords:
KEK, Mη-επείγουσα αξονική εγκεφάλου, ΚΚΓ
Index:
No
Number of index pages:
0
Contains images:
No
Number of references:
29
Number of pages:
29
File:
File access is restricted only to the intranet of UoA.

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