Κατεύθυνση Εργοσπιρομετρία και Καρδιοαναπνευστική Αποκατάσταση
Library of the School of Health Sciences

2024-12-05

2024

Drosatos Ioannis-Alexandros

Φιλίππου Αναστάσιος, Αναπληρωτής Καθηγητής, Ιατρική Σχολή, ΕΚΠΑ
Παπαζάχου Ουρανία, Επιστημονική Συνεργάτης, Ιατρική Σχολή, ΕΚΠΑ
Καρατζάνος Ελευθέριος, Επιστημονικός Συνεργάτης, Ιατρική Σχολή, ΕΚΠΑ

Η επίδραση της συστηματικής σωματικής άσκησης σε δείκτες φλεγμονής σε υγιείς ενήλικες

Greek

The effect of exercise on inflammatory markers in healthy adults

Purpose: The aim of this study is to systematically review the effects of regular exercise on classic inflammatory mediators in healthy adults.

Methods: We conducted a thorough bibliographic search in six electronic databases (Pubmed, Scopus, Sportdiscus, CINAHL, Web of Science, Cochrane Library) for the selection of randomized and non-randomized interventional trials, which compared at least one exercise intervention with a control condition in healthy adults, to test the effect of exercise on inflammatory mediators, such as CRP, IL-6, TNF-a, IL-1b.

Results: Forty-six original studies were finally included in the systematic review, some of which comprised more than one intervention arm. Most studies presented their results in a way that was suitable for the meta-analysis of the data. The conducted meta-analyses showed a significant reduction of CRP, IL-6 and TNF-a, but not IL-1b, after regular exercise. Subgroup analysis suggested that aerobic and interval exercise were the most beneficial types of exercise in reducing these inflammatory mediators.

Conclusion: Regular exercise results in a significant reduction of CRP, IL-6 and TNF-a in apparently healthy adults.

Health Sciences

Exercise, Healthy, CRP, IL-6, TNF-a, Inflammation

No

0

Yes

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62

File access is restricted until 2025-06-04.

https://pergamos.lib.uoa.gr/uoa/dl/object/3441316