Περίληψη:
The evidence concerning the possible association between physical
activity and the risk of prostate cancer is inconsistent and additional
data are needed. We examined the association between risk of prostate
cancer and physical activity at work and in leisure time in the European
Prospective Investigation into Cancer and Nutrition (EPIC) cohort. In
our study, including 127,923 men aged 20-97 years from 8 European
countries, 2,458 cases of prostate cancer were identified during 8.5
years of followup. Using the Cox proportional hazards model, we
investigated the associations between prostate cancer incidence rate and
occupational activity and leisure time activity in terms of
participation in sports, cycling, walking and gardening; a metabolic
equivalent (MET) score based on weekly time spent on the 4 activities;
and a physical activity index. MET hours per week of leisure time
activity, higher score in the physical activity index, participation in
any of the 4 leisure time activities, and the number of leisure time
activities in which the participants were active were not associated
with prostate cancer incidence. However, higher level of occupational
physical activity was associated with lower risk of advanced stage
prostate cancer (p(trend) = 0.024). In conclusion, our data support the
hypothesis of an inverse association between advanced prostate cancer
risk and occupational physical activity, but we found no support for an
association between prostate cancer risk and leisure time physical
activity. (C) 2009 UICC
Συγγραφείς:
Johnsen, Nina Fans
Tjonneland, Anne
Thomsen, Birthe L. R. and
Christensen, Jane
Loft, Steffen
Friedenreich, Christine
Key,
Timothy J.
Allen, Naomi E.
Lahmann, Petra H.
Mejlvig, Lotte
and Overvad, Kim
Kaaks, Rudolf
Rohrmann, Sabine
Boing,
Heiner
Misirli, Gesthimani
Trichopoulou, Antonia
Zylis,
Dimosthenis
Tumino, Rosario
Pala, Valeria
Bueno-de-Mesquita,
H. Bas
Kiemeney, Lambertus A.
Rodriguez Suarez, Laudina and
Gonzalez, Carlos A.
Sanchez, Maria-Jose
Maria Huerta, Jose and
Barricarte Gurrea, Aurelio
Manjer, Jonas
Wirfalt, Elisabet and
Khaw, Kay-Tee
Wareham, Nick
Boffetta, Paolo
Egevad, Lars and
Rinaldi, Sabina
Riboli, Elio
