Τίτλος:
Obstetrical brachial plexus palsy: Lessons in functional neuroanatomy
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Obstetrical branchial plexus paralysis is a serious and possibly disabling disorder. While thoroughly described as a clinical entity, much concerning its pathogenesis is still unknown. Basic science studies alongside with studies on functional neuroanatomy of peripheral and central nervous system and their interactions lead to deeper understanding of its pathology. Research concentrates on the consequences of branchial plexus traction to peripheral nerves and muscles function and viability and rehabilitation options. Changes obstetrical branchial plexus paralysis causes to central nervous systems organisation have been, to some extent, investigated. It seems that central nervous system is not "blind" after obstetrical branchial plexus paralysis but instead proceeds to remodelling so to adapt to new needs. Research indicates that both this entity and organism's response are much more complicated than previously believed. Current treatment options include microsurgery and palliative surgery but their improvement is possible by focusing on central nervous system. Current report discusses these topics and tries to reach useful conclusions. © 2013 Elsevier Ltd.
Συγγραφείς:
Johnson, E.O.
Troupis, T.
Michalinos, A.
Dimovelis, J.
Soucacos, P.N.
Λέξεις-κλειδιά:
article; autonomic nerve; avulsion injury; basement membrane; birth injury; body movement; body position; brachial plexus injury; breech extraction; cell migration; central nervous system; disease course; early intervention; hand function; hand reconstruction; Horner syndrome; human; joint contracture; joint mobility; left hemisphere; limb amputation; magnetoencephalography; microsurgery; motoneuron; nerve fiber degeneration; nerve fiber transport; nerve transection; neuroanatomy; obstetrical brachial plexus paralysis; pain receptor; palliative therapy; passive movement; perikaryon; peripheral nerve; peripheral nerve injury; priority journal; Schwann cell; secondary somatosensory cortex; sensory receptor; sensory stimulation; skin blood vessel; somatosensory cortex; spinal reflex; spinothalamic tract; stretch receptor; substantia gelatinosa; supplementary motor area; target organ; tendon transfer; thermoreceptor; body posture; brachial plexus; Brachial Plexus Neuropathies; clinical pathway; complication; elbow; female; injuries; microsurgery; newborn; Paralysis, Obstetric; pathophysiology; pregnancy; prognosis; risk factor; severity of illness index; shoulder; treatment outcome; wrist, Brachial Plexus; Brachial Plexus Neuropathies; Critical Pathways; Elbow Joint; Female; Humans; Infant, Newborn; Microsurgery; Paralysis, Obstetric; Peripheral Nerves; Pregnancy; Prognosis; Risk Factors; Severity of Illness Index; Shoulder Joint; Supination; Treatment Outcome; Wrist Joint
DOI:
10.1016/j.injury.2013.01.020
