Περίληψη:
Aim: To reveal correlations between serum lactate dehydrogenase (LDH)
levels and various clinicopathological parameters in colorectal and
gastric cancer. Materials & methods: A hospital-based case control
study was conducted by measuring serum LDH levels in 140 patients with
colorectal cancer, 40 patients with gastric cancer and 20 hospital
controls. Results: LDH levels did not differ between patients with
colorectal or gastric cancer and hospital controls. In colorectal
cancer, LDH values were significantly higher in T4, N2 and/or M1 cases,
with high specificities and negative predictive values, but low
sensitivities and positive predictive values. On the other hand, there
were no significant associations in gastric cancer. Conclusion: Serum
LDH levels are increased in T4, N2 and/or M1 colorectal cancer. Most
patients with early-stage cancer have normal LDH values, whereas in
advanced stages, some patients have increased LDH values and others have
normal values.
Συγγραφείς:
Kostakis, Ioannis D.
Vaiopoulos, Aristeidis G.
Philippou,
Anastassios
Papavassiliou, Athanasios G.
Koutsilieris, Michael
and Kouraklis, Gregory
