Clinical Outcome and Safety of Multilevel Vertebroplasty: Clinical Experience and Results

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3156587 11 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Clinical Outcome and Safety of Multilevel Vertebroplasty: Clinical
Experience and Results
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
To compare safety and efficacy of percutaneous vertebroplasty (PVP) when
treating up to three vertebrae or more than three vertebrae per session.
We prospectively compared two groups of patients with symptomatic
vertebral fractures who had no significant response to conservative
therapy. Pathologic substrate included osteoporosis (n = 77), metastasis
(n = 24), multiple myeloma (n = 13), hemangioma (n = 15), and lymphoma
(n = 1). Group A patients (n = 94) underwent PVP of up to three treated
vertebrae (n = 188). Group B patients (n = 36) underwent PVP with more
than three treated vertebrae per session (n = 220). Decreased pain and
improved mobility were recorded the day after surgery and at 12 and 24
months after surgery per clinical evaluation and the use of numeric
visual scales (NVS): the Greek Brief Pain Inventory, a linear analogue
self-assessment questionnaire, and a World Health Organization
questionnaire.
Group A presented with a mean pain score of 7.9 +/- A 1.1 NVS units
before PVP, which decreased to 2.1 +/- A 1.6, 2.0 +/- A 1.5 and 2.0 +/-
A 1.5 NVS units the day after surgery and at 12 and 24 months after
surgery, respectively. Group B presented with a mean pain score of 8.1
+/- A 1.3 NVS units before PVP, which decreased to 2.2 +/- A 1.3, 2.0
+/- A 1.5, and 2.1 +/- A 1.6 NVS units the day after surgery and at 12
and 24 months after surgery, respectively. Overall pain decrease and
mobility improvement throughout the follow-up period presented no
statistical significance neither between the two groups nor between
different underlying aetiology. Reported cement leakages presented no
statistical significance between the two groups (p = 0.365).
PVP is an efficient and safe technique for symptomatic vertebral
fractures independently of the vertebrae number treated per session.
Έτος δημοσίευσης:
2013
Συγγραφείς:
Mailli, Leto
Filippiadis, Dimitrios K.
Brountzos, Elias N. and
Alexopoulou, Efthymia
Kelekis, Nikolaos
Kelekis, Alexios
Περιοδικό:
CardioVascular and Interventional Radiology
Εκδότης:
Springer-Verlag
Τόμος:
36
Αριθμός / τεύχος:
1
Σελίδες:
183-191
Λέξεις-κλειδιά:
Vertebroplasty; Multilevel; Metastasis; Osteoporosis; Multiple myeloma
Επίσημο URL (Εκδότης):
DOI:
10.1007/s00270-012-0379-z
Το ψηφιακό υλικό του τεκμηρίου δεν είναι διαθέσιμο.