Treatment of rheumatoid arthritis with gene therapy applications: Biosafety and bioethical considerations

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:2980697 29 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Treatment of rheumatoid arthritis with gene therapy applications: Biosafety and bioethical considerations
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Rheumatoid Arthritis (RA) is an autoimmune and inflammatory disease that affects the synovium (lining that surrounds the joints), causing the immune system to attack its own healthy tissues. Treatment options, to the current day, have serious limitations and merely offer short-term alleviation to the pain. Using a theoretical exercise based on literature, a new potentially viable therapy has been proposed. The new therapy focusses on a long-term treatment of RA based on gene therapy, which is only active when inflammation of the joint occurs. This treatment will prevent side effects of systemic application of drugs. Furthermore, the benefits of this treatment for the patient from a socio-economic perspective has been discussed, focusing on the quality of life of the patent and lower costs for the society. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Έτος δημοσίευσης:
2021
Συγγραφείς:
Tsitrouli, Z.
Akritidou, M.-A.
Genitsaris, S.
van Willigen, G.
Περιοδικό:
Biotech Info
Εκδότης:
MDPI AG
Τόμος:
10
Αριθμός / τεύχος:
3
Επίσημο URL (Εκδότης):
DOI:
10.3390/biotech10030011
Το ψηφιακό υλικό του τεκμηρίου δεν είναι διαθέσιμο.