Τίτλος:
Effects of flaxseed oil supplementation on plasma adiponectin levels in dyslipidemic men
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: Dietary alpha-linolenic acid (ALA) has been associated with reduced risk of development of atherosclerosis. Adiponectin is a hormone specifically secreted by adipocytes and considered to have anti-atherogenic properties. Aim of the study: We examined the effect of increased dietary intake of ALA on plasma concentration of adiponectin. Methods: Thirty-five non-diabetic, dyslipidemic men, 38-71 years old, were randomly allocated to take either 15 ml of flaxseed oil rich in ALA (8.1 g/day; n = 18), or 15 ml of safflower oil per day, containing the equivalent n-6 fatty acid (11.2 g/day linoleic acid, LA; n = 17) (control group). The intervention period lasted for 12 weeks. Results: Plasma levels of adiponectin did not change after the increase in dietary intake of ALA in the flaxseed oil supplementation group, compared to the control group. No changes in body mass index, serum lipid concentrations, LDL density, or plasma TNF-α were found in the flaxseed oil versus the control group. Conclusions: Dietary ALA has no effect on plasma adiponectin concentration in dyslipidemic men. © 2007 Spinger.
Συγγραφείς:
Paschos, G.K.
Zampelas, A.
Panagiotakos, D.B.
Katsiougiannis, S.
Griffin, B.A.
Votteas, V.
Skopouli, F.N.
Περιοδικό:
European Journal of Nutrition
Λέξεις-κλειδιά:
adiponectin; arachidonic acid; icosapentaenoic acid; linoleic acid; linseed oil; lipid; low density lipoprotein; oleic acid; omega 6 fatty acid; palmitic acid; safflower oil; stearic acid; tocopherol; tumor necrosis factor alpha, adult; article; body mass; clinical article; clinical trial; control group; controlled clinical trial; controlled study; diet supplementation; dietary intake; dyslipidemia; human; intervention study; lipid blood level; male; protein blood level; randomized controlled trial; single blind procedure, Adiponectin; Adult; Aged; alpha-Linolenic Acid; Dietary Supplements; Humans; Hyperlipidemias; Linseed Oil; Lipids; Male; Middle Aged; Safflower Oil; Treatment Outcome, Carthamus tinctorius
DOI:
10.1007/s00394-007-0668-5
