Τίτλος:
Patterns of non-syndromic permanent tooth agenesis in a large orthodontic population
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Objective The aim of this study is to explore patterns of non-syndromic permanent tooth agenesis in a large orthodontic patient group. Design A record review was performed in various orthodontic clinics to identify white patients with non-syndromic permanent tooth agenesis, excluding 3rd molars. Four hundred and fourteen subjects fulfilled the inclusion criteria. Results In the 414 subjects with tooth agenesis, approximately 70% presented 1–2 missing teeth. Symmetric agenesis patterns were often observed in the sample (by jaw, by side, or crossed quadrants), with prevalence approaching 30% for cases with contralateral tooth agenesis within a jaw. In cases with 1 or 2 missing teeth, from the total number of potential tooth agenesis patterns in the sample, a certain part was evident, limiting the variation to 27.8% (44/158). In the entire sample, both in the maxilla and the mandible a certain incisor/premolar agenesis phenotype was observed in 59.0% of cases in isolated form. Conclusions Although there was variation in the tooth agenesis patterns, our findings suggest the involvement of particular genetic, epigenetic, and/or environmental factors in the formation of the entire dentition, which often lead to specific tooth agenesis phenotypes in cases where this process is disrupted. The present study provides a comprehensive categorization of orthodontic cases with tooth agenesis and can assist in planning future epidemiological and genetic studies. © 2017 Elsevier Ltd
Συγγραφείς:
Gkantidis, N.
Katib, H.
Oeschger, E.
Karamolegkou, M.
Topouzelis, N.
Kanavakis, G.
Περιοδικό:
ARCHIVES OF ORAL BIOLOGY
Εκδότης:
Elsevier Ireland Ltd
Λέξεις-κλειδιά:
abnormalities; adolescent; adult; anodontia; child; diagnostic imaging; female; human; incisor; male; mandible; maxilla; orthodontics; panoramic radiography; periodontal disease; premolar tooth; prevalence; Switzerland; third molar; young adult, Adolescent; Adult; Anodontia; Bicuspid; Child; Female; Humans; Incisor; Male; Mandible; Maxilla; Molar, Third; Orthodontics; Prevalence; Radiography, Panoramic; Switzerland; Tooth Loss; Young Adult
DOI:
10.1016/j.archoralbio.2017.02.020
