Effectiveness of an in-office arginine-calcium carbonate paste on dentine hypersensitivity in periodontitis patients: A double-blind, randomized controlled trial

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:2990886 12 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Effectiveness of an in-office arginine-calcium carbonate paste on dentine hypersensitivity in periodontitis patients: A double-blind, randomized controlled trial
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Aim The aim of this single-centre, two-cell, double-blind, randomized controlled clinical study was to evaluate the effectiveness of an in-office desensitizing paste containing 8% arginine and calcium carbonate in providing relief on dentine hypersensitivity immediately after scaling and root planing and its sustained relief over a 6-week period. Materials and Methods Fifty periodontitis subjects presenting hypersensitivity were subjected to scaling and root planing and in-office application of either 8% arginine and calcium carbonate desensitizing paste (25 subjects, test group) or fluoride-free prophylaxis paste (25 subjects, control group). Air-blast hypersensitivity was assessed using Schiff and Visual Analogue (VAS) scales at baseline, post-scaling, post-application, 2, 4 and 6 weeks. Results At all evaluation times, the test group presented significant % reduction in hypersensitivity relative to post-scaling (t-test, p < 0.05) (Schiff - Test: 57, 58.6, 60.2, 68; Control: 28.6, 22.2, 23, 23) (VAS - Test: 60, 55.6, 60.1, 68.4; Control: 25.9, 18.2, 20.6, 22.7) and significant % hypersensitivity difference relative to control (ancova, p < 0.05) (Schiff: 38.9, 45.9, 47.4, 57.7; VAS: 49.1, 48.9, 52.6, 61). Conclusion The single in-office application of the 8% arginine-calcium carbonate desensitizing paste after scaling and root planing provided significant immediate reduction in dentine hypersensitivity, which sustained over a 6-week period. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Έτος δημοσίευσης:
2015
Συγγραφείς:
Pepelassi, E.
Rahiotis, C.
Peponi, E.
Kakaboura, A.
Vrotsos, I.
Περιοδικό:
Journal of Clinical Periodontology
Εκδότης:
Blackwell Munksgaard
Τόμος:
42
Αριθμός / τεύχος:
1
Σελίδες:
37-45
Λέξεις-κλειδιά:
arginine; calcium carbonate; desensitizing agent; toothpaste, adolescent; adult; aged; comparative study; controlled study; dentin sensitivity; double blind procedure; female; follow up; human; male; middle aged; periodontics; periodontitis; preventive dentistry; procedures; randomized controlled trial; treatment outcome; visual analog scale; young adult, Adolescent; Adult; Aged; Arginine; Calcium Carbonate; Dental Scaling; Dentin Desensitizing Agents; Dentin Sensitivity; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Periodontal Index; Periodontitis; Root Planing; Toothpastes; Treatment Outcome; Visual Analog Scale; Young Adult
Επίσημο URL (Εκδότης):
DOI:
10.1111/jcpe.12319
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