Τίτλος:
Melan-A/Mart-1- or HMB-45-positive melanocytes are not present in calcifying cystic odontogenic tumors (calcifying odontogenic cysts): a study in 13 Caucasian patients.
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Melanin pigment and melanocytes may be found in odontogenic cysts and tumors, particularly calcifying cystic odontogenic tumor (CCOT). In the present study we investigated the immunohistochemical expression of the Melan-A/Mart-1 and HMB-45 antigens in 13 Caucasians patients with CCOT. Melan-A/Mart-1- and HMB-45-positive melanocytes were not seen in any of the cases. Our findings are in agreement with the assumption that pigmentation in odontogenic lesions may be a racial phenomenon.
Συγγραφείς:
Tosios, K.I.
Prountzos, N.
Katsoulas, N.
Koutlas, I.G.
Sklavounou-Andrikopoulou, A.
Περιοδικό:
Journal of Oral Science
Λέξεις-κλειδιά:
HMB 45 protein, human; HMB-45 protein, human; melan A; melanin; melanoma antigen, adolescent; adult; article; biosynthesis; case control study; Caucasian; child; ethnology; female; genetics; human; jaw tumor; male; melanocyte; metabolism; middle aged; odontogenic cyst; pathology, Adolescent; Adult; Case-Control Studies; Child; European Continental Ancestry Group; Female; Humans; Jaw Neoplasms; Male; MART-1 Antigen; Melanins; Melanocytes; Melanoma-Specific Antigens; Middle Aged; Odontogenic Cyst, Calcifying; Young Adult
DOI:
10.2334/josnusd.54.33