Τίτλος:
Subgingival microflora and treatment in prepubertal periodontitis associated with chronic idiopathic neutropenia
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Prepubertal periodontitis affects both primary and permanent dentition. The purpose of this study was to examine the composition of subgingival microflora of the permanent dentition in an 11-year-old Caucasian female, who had premature exfoliation of her deciduous teeth on her 5th year of age, and the response of this condition to the antibiotic therapy and supportive periodontal care. Gingival tissues were highly inflamed and alveolar bone loss was detected radiographically. The girl had experienced frequent upper respiratory tract infections, tonsilitis and recurrent otitis media. Her mother had history of early onset periodontitis associated with chronic idiopathic neutropenia. Blood chemistry tests and immunological examinations were also performed. Subgingival plaque samples were collected from the proximal sites of permanent molars, incisors, canines and maxillary premolars. 27 different microbial species were isolated from the subgingival microflora. Among the predominant species were Porphyromonas gingivalis (17.6%-7.3%), Prevotella intermedia (12.4%-4.7%), Capnocytophaga sputigena (14.4%-10.4%), Capnocytophaga ochracea (13.2%-6.9%) and Actinobacillus actinomycetemcomitans (9.3%-5.5%.). Periodontal treatment consisted of scaling, root planing in conjunction with antibiotic administration of Augmentin® 312.5 mg and Flagyl® 200 mg, each t.i.d. for 10 days. 3 weeks after the antibiotic therapy, bacterial samples were collected from the same sites. All the periodontal pathogens were recovered in lower levels and A.actinomycetemcomitans was almost eliminated in the 3-week period. The evaluation of clinical indices at 3, 6 and 12 months showed that periodontal treatment in conjunction with antibiotics was effective and rapidly followed by marked clinical improvement. The microbiological monitoring at 3, 6 and 12 months after antibiotic treatment and each time prior to supportive periodontal care, revealed that the periodontal pathogens fluctuated in low levels even 12 months after treatment and could be maintained at low level by supportive periodontal care at 3-month intervals. © Munksgaard 1998.
Συγγραφείς:
Kamma, J.J.
Lygidakis, N.A.
Nakou, M.
Περιοδικό:
Journal of Clinical Periodontology
Εκδότης:
Blackwell Munksgaard
Λέξεις-κλειδιά:
amoxicillin plus clavulanic acid; antiinfective agent; metronidazole, Actinobacillus actinomycetemcomitans; article; bacterium; Capnocytophaga; case report; child; chronic disease; classification; drug combination; drug effect; female; follow up; gingiva; human; isolation and purification; microbiology; neutropenia; periodontitis; Porphyromonas gingivalis; preventive dentistry; Prevotella intermedia; tooth plaque, Actinobacillus actinomycetemcomitans; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteria; Capnocytophaga; Child; Chronic Disease; Dental Plaque; Dental Scaling; Drug Therapy, Combination; Female; Follow-Up Studies; Gingiva; Humans; Metronidazole; Neutropenia; Periodontitis, Juvenile; Porphyromonas gingivalis; Prevotella intermedia; Root Planing
DOI:
10.1111/j.1600-051X.1998.tb02518.x
