Subgingival microflora associated with nifedipine-induced gingival overgrowth

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:2992401 20 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Subgingival microflora associated with nifedipine-induced gingival overgrowth
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The purpose of this study was to examine the composition of subgingival plaque of 140 periodontal lesions in 35 patients with cardiovascular disorders who were administered nifedipine and manifested nifedipine-induced gingival overgrowth (GO). Age was inversely associated with the GO. Plaque index and bleeding index showed a significant association with GO, while nifedipine dosage and duration of nifedipine therapy were not found to be significant predictors of GO. The gingival inflammation as expressed in the logistic regression model by the interaction term color X tone was found to be significantly associated with the GO. Statistically significant differences between the groups of comparable probing depth and different degrees of GO were detected for Propionibacterium acnes, Capnocytophaga gingivalis, Capnocytophaga ochracea, Capnocytophaga sputigena, Bacteroides gracilis, Fusobacterium mortiferum, Fusobacterium nucleatum, Fusobacterium varium and Selenomonas sputigena in deep and enlarged lesions. Significantly more frequently isolated were the bacterial species Eubacterium alactolyticum, Campylobacter concisus, C. gingivalis, C. ochracea, C. sputigena, F. mortiferum, F. nucleatum, and F. varium from the more enlarged lesions (GO > 3).
Έτος δημοσίευσης:
1998
Συγγραφείς:
Nakou, M.
Kamma, J.J.
Andronikaki, A.
Mitsis, F.
Περιοδικό:
JOURNAL OF PERIODONTOLOGY
Εκδότης:
American Academy of Periodontology
Τόμος:
69
Αριθμός / τεύχος:
6
Σελίδες:
664-669
Λέξεις-κλειδιά:
nifedipine, adult; aged; article; bacterial growth; female; gingiva hyperplasia; human; major clinical study; male; microflora; mouth flora; periodontal disease; Propionibacterium acnes; tooth plaque
Επίσημο URL (Εκδότης):
DOI:
10.1902/jop.1998.69.6.664
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