Τίτλος:
COVID-19 and ischemic stroke
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Since the onset of the COVID-19 pandemic, a substantial proportion of COVID-19 patients had documented thrombotic complications and ischemic stroke. Several mechanisms related to immune-mediated thrombosis, the renin angiotensin system and the effect of SARS-CoV-2 in cardiac and brain tissue may contribute to the pathogenesis of ischemic stroke in patients with COVID-19. Simultaneously, significant strains on global healthcare delivery, including ischemic stroke management, have made treatment of stroke in the setting of COVID-19 particularly challenging. In this review, we summarize the current knowledge on epidemiology, clinical manifestation, and pathophysiology of ischemic stroke in patients with COVID-19 to bridge the gap from bench to bedside and clinical practice during the most challenging global health crisis of the last decades. © 2021 European Academy of Neurology
Συγγραφείς:
Sagris, D.
Papanikolaou, A.
Kvernland, A.
Korompoki, E.
Frontera, J.A.
Troxel, A.B.
Gavriatopoulou, M.
Milionis, H.
Lip, G.Y.H.
Michel, P.
Yaghi, S.
Ntaios, G.
Περιοδικό:
European Journal of Paediatric Neurology
Εκδότης:
John Wiley and Sons Inc
Λέξεις-κλειδιά:
coronavirus disease 2019; global health; heart disease; human; incidence; intensive care unit; ischemic stroke; Medline; pathophysiology; practice guideline; prevalence; Review; Scopus; signal transduction; thrombosis; brain ischemia; cerebrovascular accident; complication; pandemic, Brain Ischemia; COVID-19; Humans; Ischemic Stroke; Pandemics; SARS-CoV-2; Stroke
